SCHEMBL4531076

SCHEMBL4531076

O=C(O)CCCCCCCCCCCCCCI

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.71
LMNA P02545 3/20 0.71
NFKB1 P19838 1/20 0.71
PMP22 Q01453 1/20 0.71
GPR84 Q9NQS5 8/20 0.57
FFAR1 O14842 2/20 0.57
FFAR4 Q5NUL3 2/20 0.57
SLC22A6 Q4U2R8 2/20 0.56
PPARG P37231 7/20 0.55
PPARD Q03181 7/20 0.55
PPARA Q07869 7/20 0.55
HDAC11 Q96DB2 5/20 0.55
ALDH1A1 P00352 3/20 0.55
PTPN1 P18031 3/20 0.55
TLR2 O60603 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
MEN1 O00255 2/20 0.55
FABP4 P15090 2/20 0.55
ALOX15 P16050 2/20 0.55
KMT2A Q03164 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4535092 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
SCHEMBL4521959 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
SCHEMBL4517209 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
SCHEMBL4520683 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
SCHEMBL4538012 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
SCHEMBL4517901 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
SCHEMBL4527974 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
SCHEMBL4536872 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
SCHEMBL4531334 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84
SCHEMBL4516962 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102373-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2026-04-16 US disclosed
US-20250352510-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2025-11-20 US disclosed
US-20250213522-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2025-07-03 US disclosed
EP-4578865-A2 LYMPH DIRECTING PRODRUGS Monash University (AU) 2025-07-02 EP disclosed
EP-3180349-B1 LYMPH DIRECTING PRODRUGS AND THERAPEUTIC USES THEREOF UNIV MONASH (AU) 2025-03-12 EP disclosed
CN-117164657-A Prodrugs of directed lymphatics 莫纳什大学 2023-12-05 CN disclosed
CN-117088931-A Prodrugs of directed lymphatics 莫纳什大学 2023-11-21 CN disclosed
CN-106715456-B Prodrugs of directed lymphatics 莫纳什大学 2023-08-29 CN disclosed
US-20220211664-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2022-07-07 US disclosed
US-11311512-B2 Lymph directing prodrugs MONASH UNIVERSITY (AU) 2022-04-26 US disclosed
US-20130224239-A1 ALCOHOLIC EXTRACT OF FUNGI OF GENUS CUNNINGHAMELLA AND USE THEREOF KING SAUD UNIVERSITY (SA) 2013-08-29 US disclosed
US-20090123516-A1 DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2009-05-14 US disclosed
WO-2007019478-A2 DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211664-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN TSHR 3045/4885LMNA 3766/4885NFKB1 1388/4885
US-11311512-B2 Lymph directing prodrugs LTA, ABCB11, LYN TSHR 3045/4885LMNA 3766/4885NFKB1 1388/4885
US-20130224239-A1 ALCOHOLIC EXTRACT OF FUNGI OF GENUS CUNNINGHAMELLA AND USE THEREOF ADH1C, ADH5, ERG28 TSHR 4719/4885LMNA 3792/4885NFKB1 428/4885
US-20260102373-A1 LYMPH DIRECTING PRODRUGS MALT1, CES1, LIPA TSHR 1545/4885LMNA 964/4885NFKB1 1299/4885
US-20250213522-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN TSHR 3045/4885LMNA 3766/4885NFKB1 1388/4885
US-20250352510-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN TSHR 3045/4885LMNA 3766/4885NFKB1 1388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.