Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13654568 | 0.88 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DANPEP | |
| SCHEMBL1095574 | 0.87 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DANPEP | |
| SCHEMBL12837593 | 0.84 | TAS1R3 (0.51) | PDE4APDE4BPDE4CPDE4DANPEP | |
| SCHEMBL404144 | 0.84 | TAS1R3 (0.51) | PDE4APDE4BPDE4CPDE4DANPEP | |
| SCHEMBL403455 | 0.82 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DANPEP | |
| SCHEMBL1109415 | 0.80 | ROCK2 (0.52) | ANPEPPTAFR | |
| SCHEMBL5450568 | 0.80 | CA2 (0.49) | ANPEPPPARG | |
| SCHEMBL405181 | 0.80 | CA2 (0.49) | ANPEPPPARG | |
| SCHEMBL1194409 | 0.80 | HTT (0.51) | ANPEPHTTHPGDHDAC1HDAC8 | |
| SCHEMBL403897 | 0.79 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084615-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2011-12-27 | — | — | US | disclosed |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | UNIVERSITY OF WASHINGTON (US) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | PDE4A 1478/4885PDE4B 1203/4885PDE4C 1615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.