SCHEMBL45324

SCHEMBL45324

CCCCCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.67
ALDH2 P05091 1/20 0.67
ALDH3A1 P30838 1/20 0.67
CES1 P23141 2/20 0.65
CDC25A P30304 1/20 0.65
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
CHRM2 P08172 2/20 0.59
MEN1 O00255 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2C19 P33261 1/20 0.59
KMT2A Q03164 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29418113 1.00 ALDH1A1 (0.67) ALDH1A1ALDH2ALDH3A1CES1CDC25A
SCHEMBL8863090 0.98 CES1 (0.68) ALDH1A1ALDH2ALDH3A1CES1CDC25A
SCHEMBL8863074 0.98 CES1 (0.68) ALDH1A1ALDH2ALDH3A1CES1CDC25A
SCHEMBL10731237 0.98 CES1 (0.68) ALDH1A1ALDH2ALDH3A1CES1CDC25A
SCHEMBL9626594 0.98 CES1 (0.68) ALDH1A1ALDH2ALDH3A1CES1CDC25A
SCHEMBL23731163 0.98 CES1 (0.68) ALDH1A1ALDH2ALDH3A1CES1CDC25A
SCHEMBL10725536 0.98 CES1 (0.68) ALDH1A1ALDH2ALDH3A1CES1CDC25A
SCHEMBL732925 0.98 CES1 (0.68) ALDH1A1ALDH2ALDH3A1CES1CDC25A
SCHEMBL8862943 0.98 CES1 (0.68) ALDH1A1ALDH2ALDH3A1CES1CDC25A
SCHEMBL6050334 0.98 CES1 (0.68) ALDH1A1ALDH2ALDH3A1CES1CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349678-B Continuous industrial production method of N-alkyl-nitrophthalimide 珠海派锐尔新材料有限公司 2024-04-26 CN claimed
CN-114349678-A Continuous industrial production method of N-alkyl-nitrophthalimide 珠海派锐尔新材料有限公司 2022-04-15 CN claimed
CN-112110846-A N-aryl phthalimide derivative and preparation method and application thereof 河北农业大学 2020-12-22 CN claimed
CN-108558736-A The synthetic method of N- n-pentyl phthalimides 仪征市海帆化工有限公司 2018-09-21 CN claimed
US-9895379-B2 17alpha, 21-dihydroxypregnene esters as antiandrogenic agents CASSIOPEA S.P.A. (IT) 2018-02-20 US claimed
EP-1999186-A1 POLYETHERSULFONE COMPOSITION, METHOD OF MAKING AND ARTICLES THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2008-12-10 EP claimed
WO-2007112198-A1 POLYETHERSULFONE COMPOSITION, METHOD OF MAKING AND ARTICLES THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2007-10-04 WO claimed
EP-1704176-A2 POLYETHERSULFONE COMPOSITION, METHOD OF MAKING AND ARTICLES THEREFROM GENERAL ELECTRIC COMPANY (US) 2006-09-27 EP claimed
WO-2005052029-A2 POLYETHERSULFONE COMPOSITION, METHOD OF MAKING AND ARTICLES THEREFROM GENERAL ELECTRIC COMPANY (US) 2005-06-09 WO claimed
WO-2000010976-A1 SUBSTITUTED N-ARYL-PHTHALIMIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-03-02 WO claimed
EP-0591861-B1 Reactivity control in microcrystalline coupler dispersions EASTMAN KODAK CO (US) 1999-07-28 EP claimed
US-4167638-A Process for production of 8-NHR quinolines THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1979-09-11 US claimed
US-20240336711-A1 REAGENTS AND METHODS FOR ALIPHATIC CARBON-HYDROGEN BOND FUNCTIONALIZATION THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2024-10-10 US disclosed
CN-114349678-B Continuous industrial production method of N-alkyl-nitrophthalimide 珠海派锐尔新材料有限公司 2024-04-26 CN disclosed
CN-116903517-A Preparation method of 4-nitro-N-alkylphthalimide 广东优巨先进新材料股份有限公司 2023-10-20 CN disclosed
US-11730746-B2 17beta-heterocyclyl-digitalis like compounds for the treatment of heart failure CVIE THERAPEUTICS LIMITED (TW) 2023-08-22 US disclosed
US-4106940-A N-ALKYLPHTHALIMIDE DERIVATIVE OIL FORMER AGFA-GEVAERT, A.G. (DE) 1978-08-15 US disclosed
US-3989685-A FROM PENICILLIN-1-OXIDE SHINOGI & CO., LTD. (JA) 1976-11-02 US disclosed
US-3987056-A DISPROPORTIONATION OF N-ARYL-1,2,3,6-TETRAHYDROPHTHALIMIDES PHILLIPS PETROLEUM COMPANY (US) 1976-10-19 US disclosed
US-3987056-A DISPROPORTIONATION OF N-ARYL-1,2,3,6-TETRAHYDROPHTHALIMIDES PHILLIPS PETROLEUM COMPANY (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336711-A1 REAGENTS AND METHODS FOR ALIPHATIC CARBON-HYDROGEN BOND FUNCTIONALIZATION NCF1, SHROOM3, NPM1 ALDH1A1 2010/4885ALDH2 421/4885ALDH3A1 949/4885
US-11730746-B2 17beta-heterocyclyl-digitalis like compounds for the treatment of heart failure CYP8B1, CYP24A1, NPPA ALDH1A1 3110/4885ALDH2 3215/4885ALDH3A1 2355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.