Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | ATF4 | P18848 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | GPR183 | P32249 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979662 | 0.85 | POLB (0.84) | POLBSMN1; SMN2L3MBTL1MAPTHPGD | |
| SCHEMBL793748 | 0.82 | POLB (0.75) | POLBSMN1; SMN2L3MBTL1MAPTHPGD | |
| SCHEMBL19709040 | 0.82 | HPGD (0.97) | POLBSMN1; SMN2L3MBTL1MAPTHPGD | |
| SCHEMBL6445936 | 0.82 | MEN1 (0.64) | POLBSMN1; SMN2L3MBTL1MAPTHPGD | |
| SCHEMBL19705237 | 0.81 | SMN1; SMN2 (0.67) | POLBSMN1; SMN2L3MBTL1MAPTHPGD | |
| SCHEMBL19705176 | 0.81 | HPGD (1.00) | POLBMAPTHPGDRAB9AMEN1 | |
| SCHEMBL29532316 | 0.80 | SMN1; SMN2 (0.62) | POLBSMN1; SMN2L3MBTL1MAPTHPGD | |
| SCHEMBL24998181 | 0.80 | ATF4 (0.73) | POLBSMN1; SMN2L3MBTL1ATF4ALDH1A1 | |
| SCHEMBL19692540 | 0.80 | ATF4 (1.00) | POLBSMN1; SMN2L3MBTL1MAPTHPGD | |
| SCHEMBL22221534 | 0.80 | ALDH1A1 (0.71) | POLBSMN1; SMN2L3MBTL1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306048-A1 | PHARMACEUTICAL USE OF SUBSTITUTED PIPERIDINE CARBOXAMIDES | HIGH POINT PHARMACEUTICALS, LLC | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306048-A1 | PHARMACEUTICAL USE OF SUBSTITUTED PIPERIDINE CARBOXAMIDES | HSD11B1, HSD3B1, CES1 | POLB 1203/4885SMN1; SMN2 3206/4885L3MBTL1 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.