Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014054 | 0.84 | LMNA (0.40) | ALDH1A1LMNABLMCYP3A4NFKB1 | |
| SCHEMBL1138036 | 0.81 | — | — | |
| SCHEMBL468704 | 0.79 | PPARD (0.46) | — | |
| SCHEMBL28224930 | 0.77 | PPARD (0.35) | GABBR2GABBR1GABRR1 | |
| SCHEMBL5885579 | 0.77 | PPARD (0.45) | — | |
| SCHEMBL8583417 | 0.77 | TYMS (0.31) | — | |
| SCHEMBL9982944 | 0.77 | PPARD (0.45) | — | |
| Ethylenediamine SCHEMBL5886184 | 0.76 | ALDH1A1 (0.36) | ALDH1A1LMNABLMCYP3A4NFKB1 | |
| SCHEMBL7156934 | 0.76 | PPARD (0.34) | — | |
| SCHEMBL28500058 | 0.74 | LPAR3 (0.41) | GABBR2GABBR1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952854-A2 | COMPOSITION COMPRISING NON-RADIOACTIVE METAL ION COMPLEXES WITH PHOSPHONATE COMPOUNDS FOR THE PALLIATION OF PAIN ASSOCIATED WITH DISEASES OF THE BONE AND BONE JOINTS | Mitreoak Limited (GB) | 1999-11-03 | — | — | EP | claimed |
| US-5902825-A | Composition and method for the palliation of pain associated with diseases of the bone and bone joints | MITREOAK, LTD. (US) | 1999-05-11 | — | — | US | claimed |
| WO-1998030246-A1 | COMPOSITION COMPRISING NON-RADIOACTIVE METAL ION COMPLEXES WITH PHOSPHONATE COMPOUNDS FOR THE PALLIATION OF PAIN ASSOCIATED WITH DISEASES OF THE BONE AND BONE JOINTS | MITREOAK LIMITED (GB) | 1998-07-16 | — | — | WO | claimed |
| EP-0111518-B1 | POLYMER SOLUTIONS | COURTAULDS PLC (GB) | 1986-10-29 | — | — | EP | claimed |
| US-4581072-A | CELLULOSE IN SOLVENT, WATER AND STABILIZER; FILMS; FIBERS | COURTAULDS PLC (GB) | 1986-04-08 | — | — | US | claimed |
| EP-0111518-A1 | POLYMER SOLUTIONS. | COURTAULDS PLC (GB) | 1984-06-27 | — | — | EP | claimed |
| WO-1983004415-A1 | POLYMER SOLUTIONS | COURTAULDS PLC (GB) | 1983-12-22 | — | — | WO | claimed |
| CN-109317117-B | Magnetic adsorbent, preparation method thereof and method for treating actinide waste liquid | 中国工程物理研究院核物理与化学研究所 | 2021-08-31 | — | — | CN | disclosed |
| US-20090202572-A1 | COMPOSITIONS AND METHODS FOR MODULATING BONE MASS | BAYLOR COLLEGE OF MEDICINE | 2009-08-13 | — | — | US | disclosed |
| EP-1758613-A2 | COMPOSITIONS AND METHODS FOR MODULATING BONE MASS | BAYLOR COLLEGE OF MEDICINE (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005113012-A2 | BETA ADRENERGIC DRUG CONJUGATED TO BONE TARGETING MOIETY FOR MODULATING BONE MASS | BAYLOR COLLEGE OF MEDICINE (US) | 2005-12-01 | — | — | WO | disclosed |
| EP-0952854-A2 | COMPOSITION COMPRISING NON-RADIOACTIVE METAL ION COMPLEXES WITH PHOSPHONATE COMPOUNDS FOR THE PALLIATION OF PAIN ASSOCIATED WITH DISEASES OF THE BONE AND BONE JOINTS | Mitreoak Limited (GB) | 1999-11-03 | — | — | EP | disclosed |
| US-5902825-A | Composition and method for the palliation of pain associated with diseases of the bone and bone joints | MITREOAK, LTD. (US) | 1999-05-11 | — | — | US | disclosed |
| WO-1998030246-A1 | COMPOSITION COMPRISING NON-RADIOACTIVE METAL ION COMPLEXES WITH PHOSPHONATE COMPOUNDS FOR THE PALLIATION OF PAIN ASSOCIATED WITH DISEASES OF THE BONE AND BONE JOINTS | MITREOAK LIMITED (GB) | 1998-07-16 | — | — | WO | disclosed |
| US-5401491-A | NMR contrast agents | GUERBET S.A. (FR) | 1995-03-28 | — | — | US | disclosed |
| EP-0183760-B1 | NMR CONTRAST AGENTS | GUERBET S.A. (FR) | 1992-03-18 | — | — | EP | disclosed |
| EP-0111518-B1 | POLYMER SOLUTIONS | COURTAULDS PLC (GB) | 1986-10-29 | — | — | EP | disclosed |
| EP-0183760-A1 | NMR CONTRAST AGENTS. | AMERSHAM INT PLC (GB) | 1986-06-11 | — | — | EP | disclosed |
| US-4581072-A | CELLULOSE IN SOLVENT, WATER AND STABILIZER; FILMS; FIBERS | COURTAULDS PLC (GB) | 1986-04-08 | — | — | US | disclosed |
| WO-1985005554-A1 | NMR CONTRAST AGENTS | AMERSHAM INTERNATIONAL PLC (GB) | 1985-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090202572-A1 | COMPOSITIONS AND METHODS FOR MODULATING BONE MASS | ADRB2, ADRA2A, ADRB1 | ALDH1A1 3620/4885LMNA 1169/4885BLM 4101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.