Water

Water

SCHEMBL453449

O.O.[Pd]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28303297 1.00
Water SCHEMBL11749671 1.00
Water SCHEMBL29140207 1.00
Water SCHEMBL27352815 1.00
Water SCHEMBL19762 1.00
Water SCHEMBL5066635 1.00
Water SCHEMBL23093704 0.82
Water SCHEMBL9722943 0.82
Methane SCHEMBL2579966 0.82
Water SCHEMBL1900085 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715672-B Trifluoromethyl modified macrocyclic supermolecule main body molecular cup and metal molecular cup, and preparation methods and applications thereof 上海大学 2024-11-26 CN claimed
CN-118812553-A Fluorine-containing functionalized macrocyclic supermolecule main body molecular cup and preparation method and application thereof 上海大学 2024-10-22 CN claimed
CN-116715672-A Trifluoromethyl modified macrocyclic supermolecule main body molecular cup and metal molecular cup, and preparation methods and applications thereof 上海大学 2023-09-08 CN claimed
CN-102471248-B Methods, compounds, and compositions for delivering 1,3-propan ed isulfonic acid BELLUS HEALTH INTERNATIONAL LTD 2015-01-07 CN claimed
CN-102471248-A Methods, compounds, and compositions for delivering 1,3-propan ed isulfonic acid BELLUS HEALTH INTERNATIONAL LTD 2012-05-23 CN claimed
EP-1399458-B1 AN ARYLATION METHOD FOR THE FUNCTIONALIZATION OF O-ALLYL ERYTHROMYCIN DERIVATIVES ABBOTT LAB (US) 2005-08-03 EP claimed
EP-0630365-B1 METHOD FOR PREPARING BETA-PHENYLISOSERINE AND ANALOGUES THEREOF RHONE POULENC RORER SA (FR) 1997-10-22 EP claimed
US-5608102-A Process for the preparation of β-phenylisoserine and its analogues RHONE-POULENC RORER S.A. (FR) 1997-03-04 US claimed
US-4324700-A PRECIPITATION OF HYDROXIDE, DISSOLVING WITH SULFUROUS ACID, ADSORPTION ON SUPPORT, DRYING AND FIRING JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1982-04-13 US claimed
US-6433164-B1 None US disclosed
JP-4108616-A None JP disclosed
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed
US-20250346600-A1 TRICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. 2025-11-13 US disclosed
WO-2025151449-A1 BIFUNCTIONAL P53-BINDING COMPOUNDS AND USES THEREOF PHOTYS THERAPEUTICS, INC. (US) 2025-07-17 WO disclosed
JP-H04108616-A PRODUCTION OF TETRAAMMINE PALLADIUM DIHYDROXIDE TANAKA KIKINZOKU KOGYO KK 1992-04-09 JP disclosed
US-5060672-A Synergistic scavengers for formaldehyde; unsaturated diols; cigarette smoke; anticarcinogenic agents PESCI DOHANYGYAR (HU) 1991-10-29 US disclosed
CN-1039591-A Enamine quaternary compounds and manufacture method and the application in muscle relaxant thereof BOC INC (US) 1990-02-14 CN disclosed
US-H725-H Ureido amino and imino acids, compositions and methods for use E. R. SQUIBB & SONS, INC. (US) 1990-01-02 US disclosed
EP-0152314-B1 PROCESS FOR THE PREPARATION OF CATALYSTS COMPRISING COPPER, ZINC AND ALUMINIUM, USEFUL IN THE PRODUCTION OF METHANOL FROM SYNTHESIS GAS Institut Français du Pétrole (FR) 1987-08-12 EP disclosed
EP-0152314-A2 Process for the preparation of catalysts comprising copper, zinc and aluminium, useful in the production of methanol from synthesis gas Institut Français du Pétrole (FR) 1985-08-21 EP disclosed