Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536842 | 0.97 | RAB9A (0.50) | ATMRAB9ASMN1; SMN2 | |
| SCHEMBL4537510 | 0.90 | RAB9A (0.56) | ATMRAB9AHTR7LMNATRPA1 | |
| SCHEMBL4541154 | 0.90 | RAB9A (0.56) | RAB9APAX8 | |
| SCHEMBL4542333 | 0.90 | PSEN1 (0.51) | LMNAPAX8 | |
| SCHEMBL4538787 | 0.90 | PSEN1 (0.51) | LMNAPAX8 | |
| SCHEMBL4541859 | 0.89 | RAB9A (0.54) | RAB9A | |
| SCHEMBL4539543 | 0.88 | RAB9A (0.47) | RAB9A | |
| SCHEMBL4535257 | 0.87 | RAB9A (0.53) | RAB9APAX8 | |
| SCHEMBL4535933 | 0.87 | PSEN1 (0.56) | LMNAPAX8 | |
| SCHEMBL4539052 | 0.87 | ALDH1A1 (0.47) | RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |