Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542835 | 0.90 | DPP4 (0.38) | DPP4DPP7DPP8GAAALDH1A1 | |
| SCHEMBL4537876 | 0.81 | DPP4 (0.36) | DPP4DPP7DPP8GAANR1H2 | |
| SCHEMBL1713628 | 0.81 | GPR119 (0.39) | TSHR | |
| SCHEMBL29294341 | 0.80 | HTR1A (0.47) | GAAALDH1A1POLBCYP1A2TSHR | |
| SCHEMBL21428424 | 0.80 | HTR1A (0.47) | GAAALDH1A1POLBCYP1A2TSHR | |
| SCHEMBL25179804 | 0.79 | CA2 (0.38) | ALDH1A1POLBTSHRHTTSMN1; SMN2 | |
| SCHEMBL4531819 | 0.79 | TSHR (0.33) | GAAALDH1A1POLBNR1H2NR1H3 | |
| SCHEMBL24715747 | 0.79 | ALDH1A1 (0.36) | GAAALDH1A1POLBCYP1A2CYP2C9 | |
| SCHEMBL12349916 | 0.77 | ALDH1A1 (0.47) | DPP4DPP7DPP8GAAALDH1A1 | |
| SCHEMBL13752451 | 0.77 | LIPE (0.37) | GAAALDH1A1POLBNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071691-A2 | OXINDOLE DERIVATIVES AND THE USE THEREOF AS A MEDICATION | ABBOTT GMBH & CO. KG (DE) | 2009-06-11 | — | — | WO | disclosed |