SCHEMBL4609204

SCHEMBL4609204

COc1cccc2c3c(ccc12)C=CC1(CC2CCC1C2)O3

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4538261 0.80 HTR2C (0.34)
SCHEMBL29756154 0.80 HTR2C (0.34)
SCHEMBL8136944 0.74 CA12 (0.43) PNMT
SCHEMBL20394056 0.73
SCHEMBL4533494 0.66 PNMT (0.36) PNMT
SCHEMBL31695289 0.62 HSD11B1 (0.31)
SCHEMBL12473426 0.60 CA1 (0.55) PNMT
SCHEMBL357145 0.60 CA1 (0.61) PNMT
SCHEMBL31116611 0.60 CA1 (0.61) PNMT
SCHEMBL31290574 0.57 CNR1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018229460-A1 ADDITIVE COMPOSITIONS AND USES THEREOF NIVIEST LTD (GB) 2018-12-20 WO disclosed
EP-1359170-B1 PHOTOCHROMIC CURABLE COMPOSITION AND CURED ARTICLES THEREOF TOKUYAMA CORP (JP) 2008-07-30 EP disclosed
EP-1549483-B1 METHODS FOR PREPARING COMPOSITE PHOTOCHROMIC OPHTHALMIC LENSES AND A PHOTOCHROMIC LENS & xA; SIGNET ARMORLITE INC (US) 2008-04-16 EP disclosed
US-7087195-B2 Photochromic curable composition and cured articles thereof TOKUYAMA CORPORATION (JP) 2006-08-08 US disclosed
EP-1549483-A4 METHODS FOR PREPARING COMPOSITE PHOTOCHROMIC OPHTHALMIC LENSES SIGNET ARMORLITE INC (US) 2006-05-24 EP disclosed
EP-1549483-A1 METHODS FOR PREPARING COMPOSITE PHOTOCHROMIC OPHTHALMIC LENSES SIGNET ARMORLITE, INC. (US) 2005-07-06 EP disclosed
US-6863848-B2 Methods for preparing composite photochromic ophthalmic lenses SIGNET ARMORLITE, INC. (US) 2005-03-08 US disclosed
WO-2004020183-A1 METHODS FOR PREPARING COMPOSITE PHOTOCHROMIC OPHTHALMIC LENSES SIGNET ARMORLITE, INC. (US) 2004-03-11 WO disclosed
US-20040046156-A1 Photochromic curable composition and cured articles thereof TOKUYAMA CORPORATION (JP) 2004-03-11 US disclosed
US-20040041287-A1 Methods for preparing composite photochromic ophthalmic lenses SIGNET ARMORLITE, INC. 2004-03-04 US disclosed
EP-1359170-A1 PHOTOCHROMIC CURABLE COMPOSITION AND CURED ARTICLES THEREOF TOKUYAMA CORPORATION (JP) 2003-11-05 EP disclosed
EP-0940694-B1 Photochromic curable composition TOKUYAMA CORP (JP) 2002-08-14 EP disclosed
US-6194511-B1 COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND TOKUYAMA CORPORATION (JP) 2001-02-27 US disclosed
US-6110400-A HIGH COLOR DENSITY; OPHTHALMIC LENSES TOKUYAMA CORPORATION (JP) 2000-08-29 US disclosed
EP-0940694-A1 Photochromic curable composition TOKUYAMA CORPORATION (JP) 1999-09-08 EP disclosed
EP-0773271-B1 PROCESS FOR THE PRODUCTION OF PHOTOCHROMIC PRODUCT OF CURING TOKUYAMA CORP (JP) 1999-07-21 EP disclosed
US-5910516-A PHOTOPOLYMERIZING AN UNSATURATED COMPOUND, AN ULTRAVIOLET PHOTOINITIATOR AND A PHOTOCHROMIC COMPOUND; USING A FILTER WHICH ELIMINATES THE UV LIGHT OF WAVELENGTH SHORTER THAN 400 NM. TOKUYAMA CORPORATION (JP) 1999-06-08 US disclosed
EP-0900798-A1 FULGIMIDE COMPOUNDS, USE OF THEM, AND COMPOSITIONS CONTAINING THE SAME TOKUYAMA CORPORATION (JP) 1999-03-10 EP disclosed
EP-0773271-A1 PROCESS FOR THE PRODUCTION OF PHOTOCHROMIC PRODUCT OF CURING TOKUYAMA CORPORATION (JP) 1997-05-14 EP disclosed