Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ICMT | O60725 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035725 | 0.81 | HTR2C (0.33) | HTR2CHTR2A | |
| SCHEMBL9035611 | 0.81 | HTR2C (0.31) | HTR2CHTR2A | |
| SCHEMBL9035829 | 0.81 | HTR2C (0.34) | HTR2CHTR2A | |
| SCHEMBL9035449 | 0.74 | NFKB1 (0.41) | SLC6A2SLC6A4SLC6A3CHRM2MAPT | |
| SCHEMBL4625971 | 0.70 | HTR2C (0.36) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL4538261 | 0.70 | HTR2C (0.34) | HTR2CHTR2A | |
| SCHEMBL29756154 | 0.70 | HTR2C (0.34) | HTR2CHTR2A | |
| SCHEMBL8681014 | 0.68 | ALDH1A1 (0.39) | HTR2CHTR2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL9917550 | 0.66 | HSD17B10 (0.43) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL15196167 | 0.66 | ALDH1A1 (0.37) | KDM4EMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540690-B1 | PHOTOCHROMIC CHROMENE COMPOUNDS | PPG INDUSTRIES INC (US) | 1996-05-29 | — | — | EP | disclosed |
| US-5200116-A | Which experience a reversible change from colorless to orange upon exposure to sunlight | PPG INDUSTRIES, INC. (US) | 1993-04-06 | — | — | US | disclosed |