Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 8/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 8/20 | 0.47 |
| ▸ | HTR7 | P34969 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4530220 | 0.99 | ADRA1B (0.48) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| SCHEMBL5592125 | 0.97 | ADRA1B (0.48) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL5592167 | 0.96 | ADRA1B (0.50) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| SCHEMBL5592300 | 0.94 | HTR1A (0.52) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL5592119 | 0.93 | HTR1A (0.51) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| SCHEMBL5422270 | 0.88 | HTR1A (0.49) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| SCHEMBL4522960 | 0.87 | HTR1A (0.61) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL5416920 | 0.87 | HTR1A (0.49) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| SCHEMBL5425702 | 0.87 | HTR1A (0.49) | ADRA1BADRA1AADRA1DHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL4524619 | 0.86 | HTR1A (0.60) | ADRA1BADRA1AADRA1DHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312344-A1 | ARYLPIPERAZINE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-17 | — | — | US | disclosed |
| EP-1758583-A2 | ARYLPIPERAZINE DERIVATIVES USEFUL AS ADRENERGIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005118537-A2 | ARYLPIPERAZINE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312344-A1 | ARYLPIPERAZINE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | ADRA1D, ADRB1, ADRA1A | ADRA1B 6/4885ADRA1A 3/4885ADRA1D 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.