Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565326 | 0.71 | KDM4E (0.47) | MAPTTHRBUSP2KDM4EALDH1A1 | |
| SCHEMBL20782875 | 0.70 | MAPT (1.00) | MAPTTHRBUSP2TP53LMNA | |
| SCHEMBL27931209 | 0.70 | MAPT (0.39) | MAPTTHRBUSP2KDM4EALDH1A1 | |
| SCHEMBL4539422 | 0.69 | HDAC8 (0.46) | MAPTTHRBUSP2KDM4EALDH1A1 | |
| SCHEMBL6976150 | 0.67 | ALDH1A1 (0.68) | MAPTKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL487122 | 0.66 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL1609870 | 0.65 | KDM4E (0.51) | MAPTTHRBUSP2KDM4EALDH1A1 | |
| SCHEMBL22860672 | 0.65 | MAPT (0.79) | MAPTTHRBUSP2ALDH1A1TP53 | |
| SCHEMBL6981561 | 0.65 | ALDH1A1 (0.68) | MAPTKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL28056217 | 0.65 | ALDH1A1 (0.78) | MAPTKDM4EALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638027-B1 | LOW-EXTRACTABLE THIOXANTHONES | IGM RESINS ITALIA SRL (IT) | 2016-07-13 | — | — | EP | disclosed |
| US-8933142-B2 | Low-extractable thioxanthones | LAMBERTI SPA (IT) | 2015-01-13 | — | — | US | disclosed |
| EP-2638027-A1 | LOW-EXTRACTABLE THIOXANTHONES | Lamberti SpA (IT) | 2013-09-18 | — | — | EP | disclosed |
| US-20130237628-A1 | LOW-EXTRACTABLE THIOXANTHONES | IGM RESINS ITALIA S.R.L. (IT) | 2013-09-12 | — | — | US | disclosed |
| CN-103209974-A | Low-extractable thioxanthones | LAMBERTI SPA | 2013-07-17 | — | — | CN | disclosed |
| WO-2012062692-A1 | LOW-EXTRACTABLE THIOXANTHONES | LAMBERTI SPA (IT) | 2012-05-18 | — | — | WO | disclosed |