Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538556 | 0.90 | FASN (0.32) | FASN | |
| SCHEMBL4540383 | 0.89 | HPGDS (0.31) | FASN | |
| SCHEMBL4535158 | 0.77 | KDM4E (0.34) | — | |
| SCHEMBL4542502 | 0.73 | MMP2 (0.36) | FASN | |
| SCHEMBL4565553 | 0.69 | FGFR1 (0.37) | — | |
| SCHEMBL4565401 | 0.68 | PIK3CA (0.31) | — | |
| SCHEMBL4565605 | 0.67 | MAPK14 (0.37) | FASN | |
| SCHEMBL4541263 | 0.67 | HPGDS (0.33) | — | |
| SCHEMBL4565426 | 0.66 | TGFBR1 (0.38) | — | |
| SCHEMBL4564399 | 0.66 | FASN (0.37) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637660-A1 | FATTY ACID SYNTHASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064642-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-05-18 | — | — | WO | disclosed |