Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27259595 | 0.92 | ALDH1A1 (0.52) | ALDH1A1PARP1NOS1ADORA3APP | |
| SCHEMBL29580471 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HRH4ADORA3NPC1RAB9A | |
| SCHEMBL346120 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HRH4ADORA3NPC1RAB9A | |
| SCHEMBL23190280 | 0.79 | NOS1 (0.35) | PARP1NOS1APPTLR9 | |
| Ammonia Solution, Strong SCHEMBL28148393 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HRH4ADORA3NPC1RAB9A | |
| SCHEMBL1258593 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HRH4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL780275 | 0.76 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4541045 | 0.76 | CCNB2 (0.37) | ALDH1A1HRH4PARP1NOS1APP | |
| SCHEMBL9980461 | 0.76 | ALDH1A1 (0.42) | ALDH1A1ADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1664655 | 0.76 | ALDH1A1 (0.52) | ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | MSD K.K. (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1939194-A1 | BICYCLIC AROMATIC SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | PYCR1, CHRM1, MTR | ALDH1A1 1755/4885HRH4 32/4885PARP1 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.