Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543654 | 0.85 | MEN1 (0.43) | MEN1KMT2AALDH1A1SGMS2HTR1A | |
| SCHEMBL4984839 | 0.83 | CHRM2 (0.49) | MEN1KMT2AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL4685646 | 0.79 | SLC6A9 (0.46) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4989694 | 0.74 | SLC6A2 (0.51) | MEN1KMT2AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL12804885 | 0.73 | ALPG (0.47) | MEN1KMT2AALDH1A1SGMS2HTR1A | |
| SCHEMBL4991842 | 0.72 | HDAC4 (0.44) | MEN1KMT2ASLC6A2SLC6A4TDP1 | |
| SCHEMBL4540376 | 0.71 | HTR1A (0.46) | MEN1KMT2AALDH1A1SGMS2HTR1A | |
| SCHEMBL6865381 | 0.70 | SLC6A2 (0.60) | MEN1KMT2ASLC6A2SLC6A4OPRM1 | |
| SCHEMBL4543658 | 0.70 | HTR1A (0.48) | MEN1KMT2AALDH1A1SGMS2HTR1A | |
| SCHEMBL1513365 | 0.70 | SIGMAR1 (0.61) | MEN1KMT2AALDH1A1HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084039-A2 | PROCESS FOR PRODUCING 1-[2-(DIMETHYLAMINO)-1-(4-PHENOL)ETHYL]CYCLOHEXANOL | MATRIX LABORATORIES LIMITED (IN) | 2009-07-09 | — | — | WO | claimed |
| WO-2009084039-A2 | PROCESS FOR PRODUCING 1-[2-(DIMETHYLAMINO)-1-(4-PHENOL)ETHYL]CYCLOHEXANOL | MATRIX LABORATORIES LIMITED (IN) | 2009-07-09 | — | — | WO | disclosed |