Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.53 |
| ▸ | HTR3B | O95264 | 2/20 | 0.53 |
| ▸ | HTR3A | P46098 | 2/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | GRK2 | P25098 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7369964 | 0.87 | ITGB3 (0.53) | ITGB3ITGA2BALDH1A1USP2TSHR | |
| SCHEMBL13344711 | 0.85 | ADRB1 (0.53) | ITGB3ITGA2BALDH1A1USP2TSHR | |
| SCHEMBL2285282 | 0.84 | ITGB3 (0.64) | ITGB3ITGA2BALDH1A1TSHRHSD17B10 | |
| SCHEMBL1065084 | 0.84 | ITGB3 (0.64) | ITGB3ITGA2BALDH1A1TSHRHSD17B10 | |
| SCHEMBL2302994 | 0.83 | ITGB3 (0.61) | ITGB3ITGA2BALDH1A1USP2TSHR | |
| SCHEMBL13855699 | 0.82 | ITGB3 (0.62) | ITGB3ITGA2BALDH1A1TSHRHSD17B10 | |
| SCHEMBL2282564 | 0.82 | ITGB3 (0.62) | ITGB3ITGA2BALDH1A1TSHRHSD17B10 | |
| SCHEMBL10899752 | 0.81 | ALDH1A1 (0.57) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL5237984 | 0.81 | ADRB1 (0.49) | ALDH1A1USP2TSHRHSD17B10ADRB1 | |
| SCHEMBL23256393 | 0.81 | ITGB3 (0.60) | ITGB3ITGA2BALDH1A1USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064569-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-05-18 | — | — | WO | disclosed |
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |