Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7366386 | 0.98 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2LMNAADRB1 | |
| Hydrochloric Acid SCHEMBL7500429 | 0.88 | MAPT (0.53) | ALDH1A1MAPTSMN1; SMN2LMNAADRB1 | |
| SCHEMBL1261694 | 0.86 | MAPT (0.61) | ALDH1A1MAPTSMN1; SMN2LMNACYP4F2 | |
| SCHEMBL4540918 | 0.85 | ADRB1 (0.50) | ALDH1A1MAPTADRB1HTR3EHTR3B | |
| SCHEMBL8349447 | 0.85 | ADRB1 (0.50) | ALDH1A1MAPTLMNAADRB1HTR3E | |
| SCHEMBL2370530 | 0.83 | SMN1; SMN2 (0.60) | ALDH1A1MAPTSMN1; SMN2LMNACYP4F2 | |
| SCHEMBL2650247 | 0.83 | MAPT (0.78) | ALDH1A1MAPTSMN1; SMN2LMNACYP4F2 | |
| SCHEMBL4577325 | 0.83 | ADRB1 (0.55) | ALDH1A1MAPTSMN1; SMN2LMNAADRB1 | |
| SCHEMBL10902418 | 0.81 | MAPT (0.48) | ALDH1A1MAPTSMN1; SMN2ADRB1HTR3E | |
| SCHEMBL4541029 | 0.81 | ITGB3 (0.59) | ALDH1A1MAPTLMNAADRB1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573961-B1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2023-10-25 | — | — | EP | disclosed |
| US-10987351-B2 | RORgamma modulators and uses thereof | GENFIT (FR) | 2021-04-27 | — | — | US | disclosed |
| WO-2020249064-A1 | COMPOUNDS FOR MODULATING FXR | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2020-12-17 | — | — | WO | disclosed |
| WO-2020186220-A1 | COMPOUNDS AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) | 2020-09-17 | — | — | WO | disclosed |
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10987351-B2 | RORgamma modulators and uses thereof | RORB, RORC, RORA | ALDH1A1 761/4885MAPT 4111/4885SMN1; SMN2 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.