Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28075389 | 0.98 | HSD17B1 (0.40) | HSD17B1HSD17B2ARHSD11B1ALDH1A1 | |
| SCHEMBL7179699 | 0.94 | ALDH1A1 (0.45) | HSD17B1HSD17B2ARHSD11B1ALDH1A1 | |
| SCHEMBL28876604 | 0.92 | HSD17B1 (0.37) | HSD17B1HSD17B2ARHSD11B1ALDH1A1 | |
| SCHEMBL5512574 | 0.85 | TDP1 (0.45) | HSD17B1HSD17B2ARALDH1A1TDP1 | |
| SCHEMBL10659629 | 0.85 | ALDH1A1 (0.50) | HSD17B1HSD17B2ARHSD11B1ALDH1A1 | |
| SCHEMBL10659630 | 0.85 | ALDH1A1 (0.56) | HSD17B1HSD17B2ARHSD11B1ALDH1A1 | |
| SCHEMBL2000756 | 0.82 | HSD11B1 (0.46) | HSD11B1ALDH1A1TDP1TSHRCA2 | |
| Lithium SCHEMBL5691154 | 0.79 | HSD11B1 (0.44) | HSD11B1ALDH1A1TDP1TSHRCA2 | |
| SCHEMBL4542512 | 0.78 | KIF11 (0.36) | HSD17B1HSD17B2ARCA2KIF11 | |
| SCHEMBL30368280 | 0.78 | KIF11 (0.36) | HSD17B1HSD17B2ARCA2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103435623-A | Metalloporphyrin complex and preparation method thereof, and preparation method of polycarbonate | CHANGCHUN APPLIED CHEMISTRY | 2013-12-11 | — | — | CN | claimed |
| CN-100334130-C | Preparation process of polyester carbonate with high molecular weight whole alternant structure | UNIV DALIAN SCIENCE & ENG (CN) | 2007-08-29 | — | — | CN | claimed |
| US-6525197-B1 | Producing chemical intermediates for such as epothilone or epothilone analogues synthesis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2003-02-25 | — | — | US | claimed |
| EP-1053215-B1 | METHODS FOR PREPARING MACROCYCLIC PRODUCTS BY RING-CLOSING DIINE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2002-05-22 | — | — | EP | claimed |
| EP-1053215-A1 | METHODS FOR PREPARING MACROCYCLIC PRODUCTS BY RING-CLOSING DIINE METATHESIS | Studiengesellschaft Kohle mbH (DE) | 2000-11-22 | — | — | EP | claimed |
| WO-1999040047-A1 | METHODS FOR PREPARING MACROCYCLIC PRODUCTS BY RING-CLOSING DIINE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1999-08-12 | — | — | WO | claimed |
| US-20250270188-A1 | NLRP3 INFLAMMASOME INHIBITORS | NOVARTIS AG (CH) | 2025-08-28 | — | — | US | disclosed |
| EP-4484407-A2 | (METH)ACRYLATE COMPOUND, ADDITIVE FOR OPTICAL RESIN, OPTICAL ELEMENT, AND OPTICAL DEVICE | NIKON CORPORATION (JP) | 2025-01-01 | — | — | EP | disclosed |
| US-12139471-B2 | NLRP3 inflammasome inhibitors | NOVARTIS AG (CH) | 2024-11-12 | — | — | US | disclosed |
| CN-116082563-B | (Meth) acrylate compound, optical resin additive, optical element, and optical device | 株式会社 尼康 | 2024-09-20 | — | — | CN | disclosed |
| CN-118359760-A | Optical resin, optical element, and optical device | 株式会社 尼康 | 2024-07-19 | — | — | CN | disclosed |
| CN-116082563-A | (meth) acrylate compound, optical resin additive, optical element, and optical device | 株式会社 尼康 | 2023-05-09 | — | — | CN | disclosed |
| CN-114989408-B | Solid phase catalyst for carbon dioxide/epoxy compound copolymerization and preparation method thereof | 郑州大学 | 2023-04-25 | — | — | CN | disclosed |
| US-5399645-A | Allyl substituted vinyl ethers which undergo cyclization polymerization, clear coatings for optical fibers, moldings | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | disclosed |
| US-5313003-A | Fluorinated monomers for heat resistant polymers | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-17 | — | — | US | disclosed |
| EP-0577979-A1 | Cyclopolymerizable fluor compounds, process for their preparation and thermoplastic fluoro polymers obtained therefrom | BAYER AG (DE) | 1994-01-12 | — | — | EP | disclosed |
| EP-0485837-A2 | Polycarbonate-polysiloxane copolymers with fluoralkylphenoxy end groups | BAYER AG (DE) | 1992-05-20 | — | — | EP | disclosed |
| EP-0206951-B1 | PROCESS FOR THE PERFLUOROALKYLATION OF AROMATIC DERIVATIVES | RHONE-POULENC CHIMIE (FR) | 1990-03-21 | — | — | EP | disclosed |
| EP-0206951-A2 | Process for the perfluoroalkylation of aromatic derivatives | RHONE-POULENC CHIMIE (FR) | 1986-12-30 | — | — | EP | disclosed |
| US-4347387-A | ISOMERIZATION OF 7-HYDROXYGERANYLAMINES OR 7-HYDROXYNERYLAMINES, PALLADIUM-PHOSPHINE CATALYST, ACIDOLYSIS | TAKASAGO PERFUMERY CO., LTD. (JP) | 1982-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12139471-B2 | NLRP3 inflammasome inhibitors | NLRP3, NLRP1, NOD1 | HSD17B1 1848/4885HSD17B2 2395/4885AR 1495/4885 |
| US-20250270188-A1 | NLRP3 INFLAMMASOME INHIBITORS | NLRP3, NLRP1, NOD1 | HSD17B1 1848/4885HSD17B2 2395/4885AR 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.