Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537168 | 0.97 | RAB9A (0.47) | RAB9ANPC1PAX8 | |
| SCHEMBL4536862 | 0.89 | ALDH1A1 (0.52) | RAB9ANPC1PAX8HCRTR1HCRTR2 | |
| SCHEMBL4538117 | 0.85 | FKBP1A (0.48) | RAB9ANPC1PAX8MEN1KMT2A | |
| SCHEMBL8064689 | 0.85 | RAB9A (0.43) | RAB9ANPC1PAX8HCRTR1HCRTR2 | |
| SCHEMBL8068365 | 0.84 | RAB9A (0.42) | RAB9ANPC1PAX8 | |
| SCHEMBL4537594 | 0.84 | ALDH1A1 (0.51) | NPC1MEN1KMT2A | |
| SCHEMBL4542926 | 0.84 | RAB9A (0.54) | RAB9ANPC1PAX8HCRTR1HCRTR2 | |
| SCHEMBL4541158 | 0.83 | ALDH1A1 (0.49) | MEN1KMT2A | |
| SCHEMBL4541691 | 0.82 | ALDH1A1 (0.44) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL4542326 | 0.82 | RAB9A (0.47) | RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |