Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018214 | 0.90 | CYP2D6 (0.37) | CYP2D6CHRM2CHRM1SLC22A2SLC22A1 | |
| SCHEMBL4545006 | 0.86 | BCHE (0.39) | KDM4EKCNA5CA2BCHEACHE | |
| SCHEMBL335997 | 0.76 | ESR1 (0.36) | CYP2D6CHRM2CHRM1SLC22A2SLC22A1 | |
| SCHEMBL4545011 | 0.76 | ACHE (0.40) | CYP2D6CYP2C19CYP3A4KDM4EKCNA5 | |
| SCHEMBL12379437 | 0.76 | FAAH (0.37) | CHRM2CHRM1DRD3LMNAKDM4E | |
| SCHEMBL12018213 | 0.75 | BCHE (0.45) | CYP2D6CYP2C19CYP3A4NPSR1BCHE | |
| SCHEMBL12018210 | 0.75 | AOC3 (0.39) | CYP2D6SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL10243454 | 0.72 | KDM4E (0.37) | ADRA2AADRA2BHTR2AHRH1KCNH2 | |
| SCHEMBL12018204 | 0.71 | BCHE (0.50) | CHRM2CHRM1ADRA2ADRD1SLC6A2 | |
| O-Xylene SCHEMBL5353236 | 0.71 | TSHR (0.50) | CYP2C19LMNAKDM4ECA2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120216867-A1 | FULLERENE DERIVATIVES | NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) | 2012-08-30 | — | — | US | disclosed |
| US-20120111411-A1 | FULLERENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120111411-A1 | FULLERENE DERIVATIVE | HCN2, KCNN2, TMEM109 | CYP2D6 1954/4885CHRM2 909/4885CHRM1 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.