Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | MMP1 | P03956 | 4/20 | 0.67 |
| ▸ | MMP2 | P08253 | 4/20 | 0.67 |
| ▸ | MMP9 | P14780 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.67 |
| ▸ | TTR | P02766 | 3/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | APP | P05067 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449722 | 1.00 | ALOX5 (0.67) | ALOX5HSD17B10MMP1MMP2MMP9 | |
| SCHEMBL29689081 | 0.91 | ALOX5 (0.67) | ALOX5HSD17B10MMP1MMP2MMP9 | |
| SCHEMBL14964001 | 0.91 | ALOX5 (0.67) | ALOX5HSD17B10MMP1MMP2MMP9 | |
| SCHEMBL8392954 | 0.90 | IAPP (0.74) | ALOX5HSD17B10MMP1MMP2MMP9 | |
| SCHEMBL8392957 | 0.90 | IAPP (0.74) | ALOX5HSD17B10MMP1MMP2MMP9 | |
| SCHEMBL29489693 | 0.90 | IAPP (0.74) | ALOX5HSD17B10MMP1MMP2MMP9 | |
| SCHEMBL9683152 | 0.88 | IAPP (0.67) | ALOX5HSD17B10MMP1MMP2MMP9 | |
| SCHEMBL8848008 | 0.88 | IAPP (0.67) | ALOX5HSD17B10MMP1MMP2MMP9 | |
| SCHEMBL9695794 | 0.87 | ALOX5 (0.59) | ALOX5HSD17B10MMP1MMP2MMP9 | |
| SCHEMBL9695492 | 0.86 | ALOX5 (0.58) | ALOX5HSD17B10MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |
| US-20230391711-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-12-07 | — | — | US | disclosed |
| EP-4276089-A2 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | Universite De Moncton (CA) | 2023-11-15 | — | — | EP | disclosed |
| EP-4276089-A2 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | Universite De Moncton (CA) | 2023-11-15 | — | — | EP | disclosed |
| US-11760715-B2 | Modulators of lipoxygenase and cyclooxygenase enzyme activity | UNIVERSITÉ DE MONCTON (CA) | 2023-09-19 | — | — | US | disclosed |
| US-11760715-B2 | Modulators of lipoxygenase and cyclooxygenase enzyme activity | UNIVERSITÉ DE MONCTON (CA) | 2023-09-19 | — | — | US | disclosed |
| US-11760715-B2 | Modulators of lipoxygenase and cyclooxygenase enzyme activity | UNIVERSITÉ DE MONCTON (CA) | 2023-09-19 | — | — | US | disclosed |
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | disclosed |
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | disclosed |
| US-20190119194-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIVERSITE DE MONCTON (CA) | 2019-04-25 | — | — | US | disclosed |
| US-20190119194-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIVERSITE DE MONCTON (CA) | 2019-04-25 | — | — | US | disclosed |
| US-8716191-B2 | Method of preparing an adduct | UNIVERSITE DE STRASBOURG (FR) | 2014-05-06 | — | — | US | disclosed |
| US-8716191-B2 | Method of preparing an adduct | UNIVERSITE DE STRASBOURG (FR) | 2014-05-06 | — | — | US | disclosed |
| US-20120115751-A1 | METHOD OF PREPARING AN ADDUCT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-05-10 | — | — | US | disclosed |
| US-20120115751-A1 | METHOD OF PREPARING AN ADDUCT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-05-10 | — | — | US | disclosed |
| WO-2010150103-A2 | METHOD OF PREPARING AN ADDUCT | UNIVERSITE DE STRASBOURG (FR) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760715-B2 | Modulators of lipoxygenase and cyclooxygenase enzyme activity | ALOX12, ALOX15B, ALOX5 | ALOX5 3/4885HSD17B10 216/4885MMP1 1402/4885 |
| US-20190119194-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | ALOX12, ALOX15B, ALOX5 | ALOX5 3/4885HSD17B10 216/4885MMP1 1402/4885 |
| US-20230391711-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | ALOX12, ALOX15B, ALOX5 | ALOX5 3/4885HSD17B10 216/4885MMP1 1402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.