Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 8/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.37 |
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4545281 | 0.91 | ABL1 (0.41) | NTRK1FFAR4ABL1 | |
| SCHEMBL1050669 | 0.86 | MGLL (0.40) | HDAC6AVPR1B | |
| SCHEMBL1053472 | 0.85 | MGLL (0.37) | NTRK1AVPR1BABL1 | |
| SCHEMBL1053581 | 0.85 | SLC6A9 (0.52) | NTRK1SLC6A9KCNH2CYP2D6CYP3A4 | |
| SCHEMBL1053576 | 0.76 | SLC6A9 (0.44) | SLC6A9KCNH2AVPR1BCYP2D6CYP3A4 | |
| SCHEMBL1051680 | 0.76 | HDAC8 (0.40) | HDAC6TRPM8SLC6A9KCNH2CYP2D6 | |
| SCHEMBL1050127 | 0.75 | AVPR1B (0.45) | SLC6A9KCNH2AVPR1BCYP2D6CYP3A4 | |
| SCHEMBL1050366 | 0.75 | SLC6A9 (0.46) | NTRK1SLC6A9KCNH2CYP2D6CYP3A4 | |
| SCHEMBL4545290 | 0.75 | SLC6A9 (0.43) | SLC6A9KCNH2AVPR1BCYP2D6CYP3A4 | |
| SCHEMBL4545285 | 0.74 | DDHD2 (0.42) | NTRK1SLC6A9KCNH2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120116095-A1 | GLYCINE TRANSPORTER INHIBITORS | TAISHO PHARMACEUTICAL C0., LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
| US-20120116095-A1 | GLYCINE TRANSPORTER INHIBITORS | TAISHO PHARMACEUTICAL C0., LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116095-A1 | GLYCINE TRANSPORTER INHIBITORS | SLC6A5, SLC1A2, SLC18A2 | NTRK1 3262/4885HDAC1 3873/4885HDAC6 3130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.