SCHEMBL4547142

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL963156	0.82	KDM1A (0.49)	KDM1ABRD4ATAD2EHMT2HTR4
	SCHEMBL18551063	0.81	KDM1A (0.48)	KDM1ABRD4ATAD2EHMT2HTR4
	SCHEMBL4547144	0.79	KDM1A (0.50)	KDM1ABRD4ATAD2EHMT2HTR4
	SCHEMBL18873644	0.79	KDM1A (0.47)	KDM1ABRD4ATAD2EHMT2HTR4
	SCHEMBL12395763	0.78	KDM1A (0.46)	KDM1ABRD4ATAD2EHMT2HTR4
	SCHEMBL2621574	0.78	KDM1A (0.46)	KDM1ABRD4ATAD2EHMT2HTR4
	SCHEMBL1957601	0.78	GNAI3 (0.50)	KDM1ASMN1; SMN2HSD11B1ALDH1A1PARP1
	SCHEMBL11575424	0.78	PABPC1 (0.46)	PABPC1POLBHTT
	SCHEMBL22702051	0.78	KDM1A (0.43)	KDM1ABRD4ATAD2EHMT2HTR4
	SCHEMBL27517725	0.78	LTA4H (0.53)	KDM1AHTR4SMN1; SMN2HSD11B1ACKR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.