Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27949996 | 0.88 | GNAO1 (0.52) | EPHX1EPHX2GNAI3GNAO1GNAI1 | |
| SCHEMBL18065736 | 0.82 | SMN1; SMN2 (0.47) | EPHX1EPHX2L3MBTL1MEN1KMT2A | |
| SCHEMBL1111914 | 0.80 | PABPC1 (0.47) | PABPC1DRD2EPHX1EPHX2L3MBTL1 | |
| SCHEMBL22878502 | 0.78 | PABPC1 (0.46) | PABPC1DRD2EPHX1EPHX2L3MBTL1 | |
| SCHEMBL4547142 | 0.78 | KDM1A (0.48) | PABPC1POLBHTT | |
| SCHEMBL20492763 | 0.77 | PABPC1 (0.45) | PABPC1DRD2EPHX1EPHX2L3MBTL1 | |
| SCHEMBL26412504 | 0.75 | PABPC1 (0.44) | PABPC1DRD2EPHX1EPHX2L3MBTL1 | |
| SCHEMBL27013488 | 0.75 | PABPC1 (0.44) | PABPC1DRD2EPHX1EPHX2L3MBTL1 | |
| SCHEMBL20649667 | 0.75 | EPHX1 (0.48) | PABPC1DRD2EPHX1EPHX2L3MBTL1 | |
| SCHEMBL7220679 | 0.75 | GNAI3 (0.67) | PABPC1DRD2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227917-B2 | Amine-containing lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-05 | — | — | US | disclosed |
| US-4179439-A | Rifamycins and method for their preparation | INTREPRINDEREA DE ANTIBIOTICE IASI (RO) | 1979-12-18 | — | — | US | disclosed |