SCHEMBL4547448

SCHEMBL4547448

COc1cccc(Nc2nc(Nc3cccc(CO)c3)nc(Nc3ccccc3Cl)n2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.49
SIRT5 Q9NXA8 1/20 0.49
KCNH3 Q9ULD8 2/20 0.49
NPC1 O15118 1/20 0.47
POLB P06746 1/20 0.47
RAB9A P51151 1/20 0.47
KDM4E B2RXH2 1/20 0.47
HTT P42858 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
GBA1 P04062 1/20 0.46
VSIR Q9H7M9 1/20 0.46
EGFR P00533 3/20 0.45
SRC P12931 2/20 0.45
FGFR1 P11362 2/20 0.45
ABL1 P00519 1/20 0.45
PDGFRB P09619 1/20 0.45
KIT P10721 1/20 0.45
PDGFRA P16234 1/20 0.45
MAPK14 Q16539 1/20 0.45
PIK3CA P42336 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544833 0.89 KCNH3 (0.59) SIRT1SIRT5KCNH3NPC1POLB
SCHEMBL4547555 0.88 KCNH3 (0.50) KCNH3NPC1POLBRAB9AKDM4E
SCHEMBL12530514 0.86 ABL1 (0.50) SIRT1SIRT5GBA1EGFRSRC
SCHEMBL4547449 0.86 EGFR (0.55) KCNH3NPC1POLBRAB9AKDM4E
SCHEMBL4547558 0.83 KCNH3 (0.55) KCNH3NPC1POLBRAB9AKDM4E
SCHEMBL4547556 0.82 KCNH3 (0.54) KCNH3NPC1POLBRAB9AKDM4E
SCHEMBL4547557 0.81 KCNH3 (0.53) KCNH3NPC1POLBRAB9AKDM4E
SCHEMBL6352626 0.79 L3MBTL1 (0.55) NPC1POLBHTTEGFRMAPK14
SCHEMBL14184733 0.78 NPC1 (0.48) KCNH3NPC1POLBRAB9AKDM4E
SCHEMBL4544824 0.76 KCNH3 (0.60) KCNH3NPC1POLBRAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8395727-B2 VA mode liquid crystal display device FUJIFILM CORPORATION (JP) 2013-03-12 US disclosed
US-8350999-B2 Liquid-crystal display device having particular retardations and internal hazes FUJIFILM CORPORATION (JP) 2013-01-08 US disclosed
US-20120236233-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120236234-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120236235-A1 LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120120348-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-05-17 US disclosed
US-8178601-B2 Polymer film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110311738-A1 Process of producing cellulose acylate film, cellulose acylate film, polarizing plate liquid crystal display device and optical compensation film FUJIFILM CORPORATION (JP) 2011-12-22 US disclosed
US-7990502-B2 Liquid-crystal display device FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-7981488-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-20090066887-A1 Polymer Film, Polarizing Plate Protective Film, Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-03-12 US disclosed
US-20080226888-A1 Cellulose Acylate Film, Polarizing Plate and Liquid Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080213511-A1 Optical compensation film, process for producing optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-09-04 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080198303-A1 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed