SCHEMBL45483

SCHEMBL45483

CN1CN(C)/C(=N/[N+](=O)[O-])N(Cc2cnc(Cl)s2)C1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 3/20 0.36
KMT2A Q03164 2/20 0.36
RECQL P46063 2/20 0.36
CHRNB2 P17787 2/20 0.34
CHRNA4 P43681 2/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
PKM P14618 1/20 0.33
PARG Q86W56 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL515504 1.00 LMNA (0.38) LMNAALDH1A1GAAMAPTKMT2A
SCHEMBL45484 1.00 LMNA (0.38) LMNAALDH1A1GAAMAPTKMT2A
SCHEMBL7640620 0.90 LMNA (0.36) LMNAALDH1A1GAAMAPTKMT2A
SCHEMBL7640624 0.90 LMNA (0.36) LMNAALDH1A1GAAMAPTKMT2A
SCHEMBL13168806 0.86 ALDH1A1 (0.43) LMNAALDH1A1GAAMAPTKMT2A
SCHEMBL18623488 0.86 ALDH1A1 (0.43) LMNAALDH1A1GAAMAPTKMT2A
SCHEMBL16093059 0.84 ALDH1A1 (0.41) LMNAALDH1A1GAAMAPTKMT2A
SCHEMBL10060148 0.84 LMNA (0.40) LMNAALDH1A1GAAMAPTKMT2A
SCHEMBL3909197 0.84 ALDH1A1 (0.51) LMNAALDH1A1GAAMAPTKMT2A
SCHEMBL3909196 0.84 ALDH1A1 (0.51) LMNAALDH1A1GAAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 628 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2427062-B1 A METHOD FOR INCREASING THE CROP YIELD OF AGRICULTURAL PLANTS UNDER ESSENTIALLY NON-EXISTENT PATHOGEN PRESSURE BAYER CROPSCIENCE LP (US) 2019-01-16 EP claimed
US-20180360041-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2018-12-20 US claimed
EP-2793579-B3 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI RESISTANT TO QO INHIBITORS BASF SE (DE) 2018-02-14 EP claimed
EP-2815650-B1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2016-08-17 EP claimed
US-20160227788-A1 Method for Increasing the Vigor and/or Crop Yield of Agricultural Plants Under Essentially Non-Existent Pathogen Pressure BAYER CROPSCIENCE LP 2016-08-11 US claimed
EP-2793579-B1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI RESISTANT TO QO INHIBITORS BASF SE (DE) 2016-06-08 EP claimed
EP-2731935-B1 FUNGICIDAL SUBSTITUTED 2-[2-HALOGENALKYL-4-(PHENOXY)-PHENYL]-1-[1,2,4]TRIAZOL-1-YL-ETHANOL COMPOUNDS BASF AGRO BV (NL) 2016-03-09 EP claimed
US-9271501-B2 Use of strobilurin type compounds for combating phytopathogenic fungi resistant to QO inhibitors BASF SE (DE) 2016-03-01 US claimed
EP-2744795-B1 FUNGICIDAL SUBSTITUTED 1-{2-[2-HALO-4-(4-HALOGEN-PHENOXY)-PHENYL]-2-ALKOXY-2-CYCLYL-ETHYL}-1H [1,2,4]TRIAZOLE COMPOUNDS BASF SE (DE) 2015-12-30 EP claimed
EP-2744791-B1 FUNGICIDAL SUBSTITUTED 1-{2-[2-HALO-4-(4-HALOGEN-PHENOXY)-PHENYL]-2-ALKOXY-3-METHYL-BUTYL}-1H-[1,2,4]TRIAZOLE COMPOUNDS BASF SE (DE) 2015-10-28 EP claimed
WO-2009147205-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2009-12-10 WO claimed
US-20010046994-A1 Hexahydrotriazine compounds and insecticides AGRO-KANESHO CO., LTD. (JP) 2001-11-29 US claimed
US-6187773-B1 1-(2-CHLORO-5-PYRIDYLMETHYL)-3,5-DIMETHYL-2-NITROIMINOHEXA-HYD RO-1,3,5-TRIAZINE; NONPHYTOTOXIC AGRO-KANESHO CO., LTD. (JP) 2001-02-13 US claimed
US-5965150-A CAPSULE SHELL OF WATER SOLUBLE POLYOXYETHYLENE, PLASTICIZER, OPTIONAL ADDITIVES AND FILLING OF INSECTICIDE OR NEMATOCIDE INSERTED INTO PLANT NIHON BAYER AGROCHEM K.K. (JP) 1999-10-12 US claimed
US-5951994-A COMPRISING A PESTICIDE OR FUNGICIDE AND AN ADJUVANT E.G. LIQUID ETHYLENE OXIDE ADDUCTS, A PASTY POLYOXYETHYLENE GLYCOL MODIFIED WITH LANOLIN OR BEESWAX OR A SOLID POLYOXYETHYLENE GLYCOL OR CELLULOSE; NONTOXIC; LOW DOSAGE NIHON BAYER AGROCHEM K. K. (JP) 1999-09-14 US claimed
EP-0741969-B1 Capsule preparations for plant treatment BAYER AGROCHEM KK (JP) 1998-11-18 EP claimed
EP-0741969-A2 Capsule preparations for plant treatment NIHON BAYER AGROCHEM K.K. (JP) 1996-11-13 EP claimed
EP-0734650-A2 Patch preparations for treating plants NIHON BAYER AGROCHEM K.K. (JP) 1996-10-02 EP claimed
EP-0428941-B1 Hexahydrotriazine compounds and insecticides AGRO KANESHO CO LTD (JP) 1995-05-03 EP claimed
EP-0428941-A1 Hexahydrotriazine compounds and insecticides AGRO-KANESHO CO., LTD. (JP) 1991-05-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180360041-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB LMNA 3613/4885ALDH1A1 2278/4885GAA 633/4885
US-20010046994-A1 Hexahydrotriazine compounds and insecticides DDT, H1-5, HCRTR2 LMNA 3887/4885ALDH1A1 909/4885GAA 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.