Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 2/20 | 0.55 |
| ▸ | SELE | P16581 | 2/20 | 0.55 |
| ▸ | SELL | P14151 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077432 | 1.00 | SELP (0.55) | SELPSELESELLALDH1A1FAAH | |
| SCHEMBL469507 | 1.00 | SELP (0.55) | SELPSELESELLALDH1A1FAAH | |
| SCHEMBL469656 | 0.93 | EPHX2 (0.58) | SELPSELESELLALDH1A1FAAH | |
| SCHEMBL10077351 | 0.85 | SOAT2 (0.62) | SELPSELESELLALDH1A1FAAH | |
| SCHEMBL469464 | 0.85 | SOAT2 (0.66) | SELPSELESELLALDH1A1FAAH | |
| SCHEMBL469579 | 0.84 | SOAT2 (0.68) | ALDH1A1FAAHEPHX2MAPTHDAC3 | |
| SCHEMBL1821209 | 0.82 | SMN1; SMN2 (0.54) | ALDH1A1FAAHMAPTNR1H4 | |
| SCHEMBL1821211 | 0.82 | SMN1; SMN2 (0.54) | ALDH1A1FAAHMAPTNR1H4 | |
| SCHEMBL17614786 | 0.81 | KMT2A (0.56) | ALDH1A1MAPTGAAHPGD | |
| SCHEMBL469516 | 0.81 | SOAT2 (0.71) | SELPSELESELLALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160120995-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LAB LTD (IL) | 2016-05-05 | — | — | US | disclosed |
| EP-2613779-A2 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | Medwell Laboratories Ltd. (IL) | 2013-07-17 | — | — | EP | disclosed |
| US-20130158070-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LABORATORIES LTD. (IL) | 2013-06-20 | — | — | US | disclosed |
| WO-2012032509-A2 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | MEDWELL LABORATORIES LTD. (IL) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158070-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | ALOX5, ALOX15B, ALOX15 | SELP 1429/4885SELE 574/4885SELL 864/4885 |
| US-20160120995-A1 | CONJUGATES OF POLYUNSATURATED FATTY ACIDS AND AMINE-CONTAINING COMPOUNDS AND USES THEREOF | ALOX5, ALOX15B, ALOX15 | SELP 1438/4885SELE 561/4885SELL 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.