Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | IDO1 | P14902 | 4/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259346 | 0.76 | PYGL (0.42) | MAOBKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL456348 | 0.75 | SMYD3 (0.47) | HRH4FAAH | |
| SCHEMBL11343167 | 0.74 | KHK (0.52) | KDM4EHPGDMAPTALDH1A1MAPK1 | |
| SCHEMBL9054518 | 0.73 | HTR6 (0.50) | HRH3 | |
| SCHEMBL27743091 | 0.73 | FLT3 (0.51) | MAOBIDO1FLT3KDM4EHPGD | |
| SCHEMBL11816064 | 0.73 | KHK (0.52) | HPGDMAPTALDH1A1 | |
| SCHEMBL28414304 | 0.72 | IDO1 (0.64) | MAOBIDO1FLT3KDM4EHPGD | |
| SCHEMBL6923977 | 0.72 | IDO1 (0.68) | MAOBIDO1FLT3KDM4EHPGD | |
| SCHEMBL2730199 | 0.70 | IDO1 (0.66) | MAOBIDO1FLT3KDM4EHPGD | |
| SCHEMBL7844858 | 0.70 | IDO1 (0.66) | MAOBIDO1FLT3KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2613630-A1 | HYDROGEN BOND FORMING FLUORO KETOLIDES FOR TREATING DISEASES | Cempra Pharmaceuticals, Inc. (US) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012034058-A1 | HYDROGEN BOND FORMING FLUORO KETOLIDES FOR TREATING DISEASES | CEMPRA PHARMACEUTICALS, INC. (US) | 2012-03-15 | — | — | WO | disclosed |