Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4549099 | 0.84 | MAPK1 (0.52) | RAB9AMAPK1SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL2688725 | 0.77 | RAB9A (0.51) | RAB9AMAPK1SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL4549078 | 0.71 | RAB9A (0.50) | RAB9AMAPK1SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL9787125 | 0.69 | PLA2G4B (0.67) | RAB9AMAPK1SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL13612529 | 0.68 | MAOB (0.56) | RAB9AMAPK1SMN1; SMN2L3MBTL1MAOB | |
| SCHEMBL10797162 | 0.68 | MAOB (0.67) | RAB9AMAPK1SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL13950675 | 0.68 | LMNA (0.57) | RAB9AMAPK1SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL2687877 | 0.67 | SMN1; SMN2 (0.55) | RAB9AMAPK1SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL1630447 | 0.67 | NR4A1 (0.68) | RAB9AMAPK1SMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL4364373 | 0.66 | NR4A2 (0.55) | RAB9AMAPK1SMN1; SMN2NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115942-A1 | Methods for Synthesizing Glycinols, Glyceollins I and II and Isoflavenes and Chromanes Using A Wittig Reaction, and Compositions Made Therewith | THE UNIVERSITY OF TOLEDO | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115942-A1 | Methods for Synthesizing Glycinols, Glyceollins I and II and Isoflavenes and Chromanes Using A Wittig Reaction, and Compositions Made Therewith | UGGT1, GCG, UGT8 | RAB9A 4107/4885MAPK1 2157/4885SMN1; SMN2 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.