Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930368 | 0.76 | GAA (0.46) | POLBHIF1ALMNAHPGDHSD17B10 | |
| SCHEMBL18066938 | 0.75 | LMNA (0.50) | POLBRECQLESR2HIF1ALMNA | |
| SCHEMBL4549636 | 0.72 | CA1 (0.37) | POLBRECQLESR2 | |
| SCHEMBL197382 | 0.71 | RAD51 (0.41) | HIF1ALMNAHPGDHSD17B10 | |
| SCHEMBL2840799 | 0.71 | HPGD (0.34) | RECQLHIF1ALMNAHPGDHSD17B10 | |
| SCHEMBL4549634 | 0.70 | FOLH1 (0.45) | HPGD | |
| SCHEMBL32679848 | 0.68 | ALDH1A1 (0.39) | POLBRECQLHIF1ALMNAHPGD | |
| SCHEMBL360272 | 0.68 | ALDH1A1 (0.39) | POLBRECQLHIF1ALMNAHPGD | |
| SCHEMBL27704140 | 0.68 | L3MBTL1 (0.45) | — | |
| SCHEMBL8930369 | 0.68 | MAPT (0.47) | POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895118-B2 | Negative dispersion retardation plate and achromatic circular polarizer | CRYSOPTIX K.K. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20140334002-A1 | PATTERNED RETARDER | CRYSOPTIX KK (JP) | 2014-11-13 | — | — | US | disclosed |
| US-20120113380-A1 | NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER | CRYSOPTIX KK (JP) | 2012-05-10 | — | — | US | disclosed |