SCHEMBL4551243

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4540828	0.90	MAP2 (0.45)	MAP2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL5663854	0.90	MAP2 (0.50)	MAP2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL4329236	0.85	TUBB4A (0.52)	MAP2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL5662948	0.85	PTGS2 (0.39)	MAP2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL4409843	0.83	TUBB4A (0.55)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL4551399	0.82	TUBB4A (0.42)	MAP2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL30039524	0.81	TUBB4A (0.54)	MAP2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL4550554	0.80	MAP2 (0.38)	MAP2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL4551526	0.79	KIF11 (0.46)	MAP2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL4543171	0.77	CA1 (0.37)	MAP2TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.