SCHEMBL4551399

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4329236	0.88	TUBB4A (0.52)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL4551526	0.86	KIF11 (0.46)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL30039524	0.86	TUBB4A (0.54)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL8938372	0.86	TUBB4A (0.51)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL4543171	0.84	CA1 (0.37)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL5724628	0.83	TUBB4A (0.38)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL4544037	0.83	ALDH1A1 (0.53)	CA1CA2KDM4ENPC1ALDH1A1
	SCHEMBL4541894	0.83	CA1 (0.38)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL4551243	0.82	MAP2 (0.38)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL5662948	0.82	PTGS2 (0.39)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.