Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10904297 | 0.84 | ALOX5 (1.00) | ALOX5PKMMEN1KMT2AMAPT | |
| SCHEMBL455113 | 0.80 | ALOX5 (0.76) | ALOX5PKMALDH1A1MEN1KMT2A | |
| SCHEMBL11340446 | 0.79 | PKM (0.56) | ALOX5PKMALDH1A1MEN1KMT2A | |
| SCHEMBL3050069 | 0.79 | MEN1 (0.67) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL15962026 | 0.78 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL4745815 | 0.78 | ALOX5 (0.71) | ALOX5PKMALDH1A1MEN1KMT2A | |
| SCHEMBL2646586 | 0.77 | ALOX5 (0.62) | ALOX5PKMALDH1A1MEN1KMT2A | |
| SCHEMBL7713793 | 0.77 | ALOX5 (0.73) | ALOX5PKMALDH1A1MEN1KMT2A | |
| SCHEMBL4956741 | 0.77 | CYP1A2 (0.56) | ALOX5ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8299418 | 0.77 | CYP1A2 (0.48) | ALOX5ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | claimed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | claimed |
| US-20120064601-A1 | Chromatography Membranes for the Purification of Chiral Compounds | NATRIX SEPARATIONS INC. (CA) | 2012-03-15 | — | — | US | claimed |
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | disclosed |
| US-20120064601-A1 | Chromatography Membranes for the Purification of Chiral Compounds | NATRIX SEPARATIONS INC. (CA) | 2012-03-15 | — | — | US | disclosed |