Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745790 | 0.88 | ALOX5 (0.64) | ALOX5MEN1KMT2APOLBNPC1 | |
| SCHEMBL10904297 | 0.84 | ALOX5 (1.00) | ALOX5MEN1KMT2APOLBNPC1 | |
| SCHEMBL4748961 | 0.82 | CYP2D6 (0.65) | ALOX5POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL4749308 | 0.81 | LMNA (0.62) | ALOX5MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4746373 | 0.80 | ALOX5 (0.71) | ALOX5MEN1KMT2APOLBNPC1 | |
| SCHEMBL11778443 | 0.79 | ALOX5 (0.65) | ALOX5MEN1KMT2APOLBNPC1 | |
| SCHEMBL30069319 | 0.78 | ALDH1A1 (0.69) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL1969093 | 0.78 | ALDH1A1 (0.69) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL4749787 | 0.78 | ALOX5 (0.57) | ALOX5MEN1KMT2APOLBNPC1 | |
| SCHEMBL455174 | 0.78 | ALOX5 (0.72) | ALOX5MEN1KMT2APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |