Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551745 | 1.00 | TERT (0.46) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL15700832 | 0.90 | EPHX1 (0.52) | PPARDMAPTFAAHKMT2AMEN1 | |
| SCHEMBL5694900 | 0.88 | FAAH (0.51) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL3767446 | 0.86 | ALOX15 (0.47) | FAAHALOX15SLC6A5 | |
| SCHEMBL3767450 | 0.86 | ALOX15 (0.47) | FAAHALOX15SLC6A5 | |
| SCHEMBL1941195 | 0.85 | CTSK (0.46) | CYP1A2MAPTCYP2C19CYP2C9TP53 | |
| SCHEMBL1941197 | 0.85 | CTSK (0.46) | CYP1A2MAPTCYP2C19CYP2C9TP53 | |
| SCHEMBL4758572 | 0.83 | TERT (0.53) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL4758573 | 0.83 | TERT (0.53) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL28124095 | 0.83 | ZDHHC7 (0.49) | PPARDMAPTFAAHKMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1629000-B1 | MACROCYCLIC ISOQUINOLINE PEPTIDE INHIBITORS OF HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2009-02-18 | — | — | EP | disclosed |