Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767450 | 1.00 | ALOX15 (0.47) | ALOX15FAAHPLA2G10SLC6A5LPAR3 | |
| SCHEMBL4551744 | 0.86 | TERT (0.46) | ALOX15FAAHSLC6A5 | |
| SCHEMBL4551745 | 0.86 | TERT (0.46) | ALOX15FAAHSLC6A5 | |
| SCHEMBL5694900 | 0.84 | FAAH (0.51) | ALOX15FAAHSLC6A5 | |
| SCHEMBL1941197 | 0.81 | CTSK (0.46) | — | |
| SCHEMBL1941195 | 0.81 | CTSK (0.46) | — | |
| SCHEMBL4758573 | 0.80 | TERT (0.53) | ALOX15FAAHPLA2G10SLC6A5 | |
| SCHEMBL4758572 | 0.80 | TERT (0.53) | ALOX15FAAHPLA2G10SLC6A5 | |
| SCHEMBL1942212 | 0.79 | EPHX2 (0.45) | FAAHSLC6A5LPAR3 | |
| SCHEMBL6025142 | 0.79 | SLC6A5 (0.41) | ALOX15FAAHSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033654-B1 | Process for resolving a mixture of alkyl ester enantiomers using an enzyme | BRISTOL MYERS SQUIBB CO (US) | 2012-05-16 | — | — | EP | disclosed |
| EP-2033654-A1 | Macrocyclic isoquinoline peptide inhibitors of hepatitis c virus | Bristol-Myers Squibb Company (US) | 2009-03-11 | — | — | EP | disclosed |
| EP-1629000-B1 | MACROCYCLIC ISOQUINOLINE PEPTIDE INHIBITORS OF HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2009-02-18 | — | — | EP | disclosed |