Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19009140 | 0.78 | CYP19A1 (0.36) | CYP19A1KDM4ELMNACYP3A4TSHR | |
| SCHEMBL19009143 | 0.76 | KCNH2 (0.45) | CYP19A1NOS2 | |
| SCHEMBL21690815 | 0.76 | CYP19A1 (0.33) | CYP19A1KDM4ELMNACYP3A4TSHR | |
| SCHEMBL17858892 | 0.74 | NOS2 (0.36) | CYP19A1KDM4ELMNACYP3A4TSHR | |
| SCHEMBL10841047 | 0.73 | CYP19A1 (0.33) | CYP19A1KDM4ELMNACYP3A4TSHR | |
| SCHEMBL12678552 | 0.73 | NOS2 (0.44) | CYP19A1KDM4ELMNACYP3A4TSHR | |
| SCHEMBL3182612 | 0.73 | ALDH1A1 (0.48) | CYP19A1KDM4ELMNACYP3A4TSHR | |
| SCHEMBL18647537 | 0.71 | NOS3 (0.39) | CYP19A1KDM4ELMNACYP3A4TSHR | |
| SCHEMBL255651 | 0.71 | — | — | |
| SCHEMBL25913119 | 0.69 | CYP19A1 (0.31) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121600-A2 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | Boehringer Ingelheim International GmbH (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008099000-A2 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-21 | — | — | WO | disclosed |