Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45848 | 0.86 | TP53 (0.33) | NOS3NOS2CYP1A2POLBSLC5A2 | |
| SCHEMBL12356544 | 0.82 | KCNH2 (0.45) | CYP19A1KDM4ELMNACYP3A4KCNH2 | |
| SCHEMBL19009143 | 0.82 | KCNH2 (0.45) | CYP19A1NOS2KCNH2SLC5A2 | |
| SCHEMBL17858892 | 0.80 | NOS2 (0.36) | CYP19A1NOS3NOS1NOS2KDM4E | |
| SCHEMBL12678552 | 0.78 | NOS2 (0.44) | CYP19A1NOS3NOS1NOS2KDM4E | |
| SCHEMBL4553008 | 0.78 | CYP19A1 (0.33) | CYP19A1NOS3NOS1NOS2KDM4E | |
| SCHEMBL10841047 | 0.78 | CYP19A1 (0.33) | CYP19A1NOS3NOS1NOS2KDM4E | |
| SCHEMBL3182612 | 0.78 | ALDH1A1 (0.48) | CYP19A1NOS3NOS1NOS2KDM4E | |
| SCHEMBL21690815 | 0.77 | CYP19A1 (0.33) | CYP19A1NOS3NOS1NOS2KDM4E | |
| SCHEMBL18647537 | 0.77 | NOS3 (0.39) | CYP19A1NOS3NOS1NOS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174826-A1 | DONOR-ACCEPTOR POLYMERS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174826-A1 | DONOR-ACCEPTOR POLYMERS | TST, ETFA, SQOR | CYP19A1 2200/4885NOS3 1252/4885NOS1 1919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.