Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylethyl Alcohol SCHEMBL27464884 | 0.87 | TDP1 (0.76) | FFAR1TDP1KEAP1HDAC1ALDH1A1 | |
| Phenethylamine SCHEMBL154732 | 0.85 | TAAR1 (0.73) | TDP1ALDH1A1MAOAMAOBSMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL10839772 | 0.85 | TDP1 (0.71) | FFAR1TDP1KEAP1HDAC1ALDH1A1 | |
| Hydrogen Peroxide SCHEMBL10839871 | 0.85 | TDP1 (0.71) | FFAR1TDP1KEAP1HDAC1ALDH1A1 | |
| Hydrocinnamyl Alcohol SCHEMBL28276928 | 0.84 | TDP1 (0.56) | TDP1KEAP1HDAC1MAOAMAOB | |
| SCHEMBL9421220 | 0.83 | MAOA (0.56) | FFAR1TDP1KEAP1ALDH1A1MAOA | |
| Phenyl Propionic Acid SCHEMBL6420576 | 0.82 | KEAP1 (0.79) | FFAR1TDP1KEAP1HDAC1ALDH1A1 | |
| SCHEMBL9741303 | 0.82 | ALDH1A1 (0.69) | FFAR1TDP1KEAP1ALDH1A1MAOA | |
| SCHEMBL62125 | 0.82 | ALDH1A1 (0.69) | FFAR1TDP1KEAP1ALDH1A1MAOA | |
| Benzene SCHEMBL3440179 | 0.82 | ALDH1A1 (0.69) | FFAR1TDP1KEAP1ALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115494145-A | Detection method for crude oil maturity and application of N-substituted thiophene organic salt | 中国石油天然气股份有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-115651206-A | Cage-shaped synthetic supramolecular material, preparation method and application thereof | 广州大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-115651206-A | Cage-shaped synthetic supramolecular material, preparation method and application thereof | 广州大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-115494145-A | Detection method for crude oil maturity and application of N-substituted thiophene organic salt | 中国石油天然气股份有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-111595932-A | Method for separating and analyzing trace metalloporphyrin in condensate oil | 中国石油天然气股份有限公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-111574402-A | Preparation method of fluorescent material | 江苏畅鸿新材料科技有限公司 | 2020-08-25 | — | — | CN | disclosed |
| US-20090105347-A1 | THYRONAMINE DERIVATIVES AND ANALOGS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-23 | — | — | US | disclosed |
| CN-101289428-A | Biaryl substituted triazoles as sodium channel blockers | MERCK & CO INC (US) | 2008-10-22 | — | — | CN | disclosed |
| US-7355079-B2 | Thyronamine derivatives and analogs and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-04-08 | — | — | US | disclosed |
| US-7321065-B2 | Thyronamine derivatives and analogs and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-01-22 | — | — | US | disclosed |
| EP-1625111-A4 | THYRONAMINE DERIVATIVES AND ANALOGS AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2007-04-25 | — | — | EP | disclosed |
| CN-1898198-A | Alpha-hydroxy amides as bradykinin antagonists or inverse agonists | MERCK & CO INC (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1788002-A | Biaryl substituted triazoles as sodium channel blockers | MERCK & CO INC (US) | 2006-06-14 | — | — | CN | disclosed |
| US-20060035980-A1 | Thyronamine derivatives and analogs and methods of use thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-02-16 | — | — | US | disclosed |
| EP-1625111-A2 | THYRONAMINE DERIVATIVES AND ANALOGS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-02-15 | — | — | EP | disclosed |
| US-20050096485-A1 | Thyronamine derivatives and analogs and methods of use thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-05-05 | — | — | US | disclosed |
| WO-2004093800-A2 | THYRONAMINE DERIVATIVES AND ANALOGS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105347-A1 | THYRONAMINE DERIVATIVES AND ANALOGS AND METHODS OF USE THEREOF | TPO, TSHR, THRB | FFAR1 1840/4885TDP1 1237/4885KEAP1 3010/4885 |
| US-20060035980-A1 | Thyronamine derivatives and analogs and methods of use thereof | TPO, TSHR, THRB | FFAR1 1794/4885TDP1 989/4885KEAP1 3047/4885 |
| US-20050096485-A1 | Thyronamine derivatives and analogs and methods of use thereof | TPO, TSHR, THRB | FFAR1 1840/4885TDP1 1237/4885KEAP1 3010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.