Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | RAD1 | O60671 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487705 | 0.83 | ALOX5AP (0.41) | POLBMAPTALDH1A1MEN1TSHR | |
| SCHEMBL4556987 | 0.83 | ALOX5AP (0.41) | POLBMAPTALDH1A1MEN1TSHR | |
| SCHEMBL16495014 | 0.78 | HSD11B1 (0.44) | MAPTALDH1A1TSHRKDM4ECA1 | |
| SCHEMBL3190051 | 0.77 | CES2 (0.52) | ALDH1A1MEN1TSHRKMT2AATM | |
| SCHEMBL3204890 | 0.77 | PDE2A (0.43) | ALDH1A1MEN1TSHRKMT2AATM | |
| SCHEMBL153434 | 0.76 | CYP1A1 (0.44) | POLBMAPTMEN1TSHRKMT2A | |
| SCHEMBL9657344 | 0.76 | RAD1 (0.41) | RAD1P2RY6ENPP2 | |
| SCHEMBL6853258 | 0.75 | POLB (0.42) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1363127 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MEN1TSHRKMT2AATM | |
| Hydrochloric Acid SCHEMBL28320494 | 0.75 | PDE2A (0.42) | ALDH1A1MEN1TSHRKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150247863-A1 | DERIVATIVES OF 1,2-DIHYDRO-7-HYDROXYQUINOLINES CONTAINING FUSED RINGS | Life Technologies Corporation | 2015-09-03 | — | — | US | disclosed |
| US-20150247863-A1 | DERIVATIVES OF 1,2-DIHYDRO-7-HYDROXYQUINOLINES CONTAINING FUSED RINGS | Life Technologies Corporation | 2015-09-03 | — | — | US | disclosed |
| US-20140356873-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | LIFE TECHNOLOGIES CORP (US) | 2014-12-04 | — | — | US | disclosed |
| US-20140356873-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | LIFE TECHNOLOGIES CORP (US) | 2014-12-04 | — | — | US | disclosed |
| US-8846925-B2 | Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings | Life Technologies Corporation (US) | 2014-09-30 | — | — | US | disclosed |
| US-8846925-B2 | Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings | Life Technologies Corporation (US) | 2014-09-30 | — | — | US | disclosed |
| US-20120315661-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | Life Technologies Corporation (US) | 2012-12-13 | — | — | US | disclosed |
| US-20120315661-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | Life Technologies Corporation (US) | 2012-12-13 | — | — | US | disclosed |
| US-8183375-B2 | Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings | Life Technologies Corporation (US) | 2012-05-22 | — | — | US | disclosed |
| US-8183375-B2 | Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings | Life Technologies Corporation (US) | 2012-05-22 | — | — | US | disclosed |
| US-20110027800-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | Life Technologies Corporation (US) | 2011-02-03 | — | — | US | disclosed |
| US-20110027800-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | Life Technologies Corporation (US) | 2011-02-03 | — | — | US | disclosed |
| US-7816519-B2 | longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond; fluorescent dyes, chemically reactive dyes, dye-conjugates; use of such dyes in staining samples and detecting ligands | Life Technologies Corporation (US) | 2010-10-19 | — | — | US | disclosed |
| US-7816519-B2 | longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond; fluorescent dyes, chemically reactive dyes, dye-conjugates; use of such dyes in staining samples and detecting ligands | Life Technologies Corporation (US) | 2010-10-19 | — | — | US | disclosed |
| US-20070093652-A1 | longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond; fluorescent dyes, chemically reactive dyes, dye-conjugates; use of such dyes in staining samples and detecting ligands | INVITROGEN CORPORATION (US) | 2007-04-26 | — | — | US | disclosed |
| US-20070093652-A1 | longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond; fluorescent dyes, chemically reactive dyes, dye-conjugates; use of such dyes in staining samples and detecting ligands | INVITROGEN CORPORATION (US) | 2007-04-26 | — | — | US | disclosed |
| US-7169922-B2 | Longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond | INVITROGEN CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169922-B2 | Longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond | INVITROGEN CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110027800-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | CYP3A7, UGT1A7, UGT2B7 | POLB 4476/4885MAPT 3476/4885ALDH1A1 45/4885 |
| US-20070093652-A1 | longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond; fluorescent dyes, chemically reactive dyes, dye-conjugates; use of such dyes in staining samples and detecting ligands | CYP3A4, CYP3A5, UGT1A4 | POLB 4565/4885MAPT 2916/4885ALDH1A1 140/4885 |
| US-20150247863-A1 | DERIVATIVES OF 1,2-DIHYDRO-7-HYDROXYQUINOLINES CONTAINING FUSED RINGS | CYP3A7, UGT1A7, UGT2B7 | POLB 4476/4885MAPT 3476/4885ALDH1A1 45/4885 |
| US-20140356873-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | CYP3A7, UGT1A7, UGT2B7 | POLB 4476/4885MAPT 3476/4885ALDH1A1 45/4885 |
| US-20120315661-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | CYP3A7, UGT1A7, UGT2B7 | POLB 4476/4885MAPT 3476/4885ALDH1A1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.