Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557508 | 1.00 | ACE (0.44) | ACEPPARGPPARAGAASMN1; SMN2 | |
| SCHEMBL15764466 | 0.75 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL4566374 | 0.73 | ACE (0.70) | ACEPPARGPPARAGAA | |
| SCHEMBL4566373 | 0.73 | ACE (0.70) | ACEPPARGPPARAGAA | |
| SCHEMBL4459598 | 0.72 | ACE (0.56) | ACEPPARGPPARAGAASMN1; SMN2 | |
| SCHEMBL4457146 | 0.71 | — | — | |
| SCHEMBL15764465 | 0.70 | KIF11 (0.43) | — | |
| SCHEMBL4458236 | 0.68 | ACE (0.54) | ACEPPARGPPARAGAASMN1; SMN2 | |
| SCHEMBL4458242 | 0.68 | ACE (0.54) | ACEPPARGPPARAGAASMN1; SMN2 | |
| SCHEMBL4455547 | 0.68 | KDM4E (0.38) | SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |