Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | KDM6B | O15054 | 1/20 | 0.54 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.50 |
| ▸ | WNT3A | P56704 | 2/20 | 0.50 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4908980 | 0.82 | KMT2A (0.82) | DEGS1KMT2AMEN1SLC6A2SLC6A3 | |
| SCHEMBL4783915 | 0.80 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL20250651 | 0.79 | ELOVL1 (0.65) | DEGS1KMT2AMEN1SLC6A2SLC6A3 | |
| SCHEMBL6683882 | 0.79 | LMNA (0.67) | GAACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2492016 | 0.79 | EPHX2 (0.58) | DEGS1KMT2AMEN1KDM6BKDM4D | |
| SCHEMBL14920768 | 0.78 | CHRNB2 (0.51) | HSD17B10EPHX2GAACHRNB2CHRNB4 | |
| SCHEMBL8987947 | 0.77 | CACNA1I (0.45) | KMT2AMEN1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL6361625 | 0.77 | SMN1; SMN2 (0.47) | HSD17B10EPHX2ALDH1A1GAAMAPT | |
| SCHEMBL2685376 | 0.77 | CHRNB2 (0.47) | EPHX2GAACHRNB2CHRNB4CHRNA3 | |
| Benzene SCHEMBL11566961 | 0.77 | EPHX2 (0.76) | KMT2AMEN1KDM6BKDM4DKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | claimed |