SCHEMBL4557712

SCHEMBL4557712

COc1ccc(=O)n(O)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.41
NQO2 P16083 3/20 0.41
IDH1 O75874 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
DAO P14920 1/20 0.39
MAPT P10636 6/20 0.38
KDM4E B2RXH2 5/20 0.38
KMT2A Q03164 4/20 0.38
ALDH1A1 P00352 3/20 0.38
POLB P06746 2/20 0.38
MAPK1 P28482 2/20 0.38
HTT P42858 2/20 0.38
GAA P10253 2/20 0.38
LMNA P02545 1/20 0.38
PABPC1 P11940 1/20 0.38
XBP1 P17861 1/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3286114 0.70 CA1 (0.52) CA1CA2CA7CA9MAPT
SCHEMBL9499742 0.68 DAO (0.51) CYP19A1NQO2IDH1CA1CA2
SCHEMBL20593880 0.67 HAAO (0.50) KDM4EALDH1A1ALOX15HPGDHSD17B10
SCHEMBL17885904 0.63 CA12 (0.43) CA1CA2CA7CA9DAO
SCHEMBL29131019 0.62 CYP19A1 (0.44) CYP19A1NQO2DAOMAPTKDM4E
SCHEMBL14438070 0.62 CYP19A1 (0.61) CYP19A1NQO2MAPTKDM4EALDH1A1
SCHEMBL3278153 0.62 ALDH1A1 (0.60) MAPTKDM4EKMT2AALDH1A1POLB
SCHEMBL1635785 0.60 ACHE (0.52) CA1CA2CA7CA9MAPT
SCHEMBL29793327 0.60 ACHE (0.52) CA1CA2CA7CA9MAPT
SCHEMBL11134106 0.59 MAPT (0.73) CA1CA2CA7CA9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365945-B2 Urinary microbiomic profiling Convergent Genomics, Inc. (US) 2025-07-22 US claimed
US-20250009891-A1 CONJUGATES OF MONOCYCLIC BETA-LACTAMS AND SIDEROPHORE MIMETICS UNIVERSITY OF NOTRE DAME DU LAC 2025-01-09 US claimed
EP-0138420-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING 1-HYDROXYPYRID-2-ONE DERIVATIVES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1989-11-29 EP claimed
US-20250305052-A1 URINARY MICROBIOMIC PROFILING Convergent Genomics, Inc. 2025-10-02 US disclosed
US-12365945-B2 Urinary microbiomic profiling Convergent Genomics, Inc. (US) 2025-07-22 US disclosed
US-12344897-B2 Urinary microbiomic profiling Convergent Genomics, Inc. (US) 2025-07-01 US disclosed
US-20250009891-A1 CONJUGATES OF MONOCYCLIC BETA-LACTAMS AND SIDEROPHORE MIMETICS UNIVERSITY OF NOTRE DAME DU LAC 2025-01-09 US disclosed
US-12098364-B2 Methods and compositions for collection and preservation of biologicals Convergent Genomics, Inc. (US) 2024-09-24 US disclosed
EP-3606325-B1 RATIONAL DESIGN OF MICROBIAL-BASED BIOTHERAPEUTICS GUSTO GLOBAL LLC (US) 2024-09-04 EP disclosed
US-20240254558-A1 URINARY MICROBIOMIC PROFILING Convergent Genomics, Inc. 2024-08-01 US disclosed
EP-4405342-A2 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-31 EP disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 WO disclosed
EP-2074240-A2 METHOD OF INHIBITING CORROSION IN STORAGE AND TRANSPORT VESSELS Nalco Company (US) 2009-07-01 EP disclosed
WO-2008060782-A2 METHOD OF INHIBITING CORROSION IN STORAGE AND TRANSPORT VESSELS NALCO COMPANY (US) 2008-05-22 WO disclosed
US-20080083435-A1 METHOD OF INHIBITING CORROSION IN STORAGE AND TRANSPORT VESSELS ECOLAB USA INC. 2008-04-10 US disclosed
EP-0138421-B1 HYDROXYPYRIDONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1990-12-05 EP disclosed
EP-0138420-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING 1-HYDROXYPYRID-2-ONE DERIVATIVES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1989-11-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250009891-A1 CONJUGATES OF MONOCYCLIC BETA-LACTAMS AND SIDEROPHORE MIMETICS MGAM, OPRM1, BPGM CYP19A1 1315/4885NQO2 1891/4885IDH1 527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.