Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491577 | 0.82 | KMT2A (0.40) | ALOX15HDAC8ALDH1A1MAPTLMNA | |
| SCHEMBL4493246 | 0.81 | ALDH1A1 (0.39) | ALOX15HDAC8ALDH1A1KMT2ACA12 | |
| SCHEMBL11847765 | 0.71 | ALDH1A1 (0.46) | ALOX15HDAC8ALDH1A1MAPTLMNA | |
| SCHEMBL6884900 | 0.64 | KMT2A (0.47) | ALDH1A1LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL20353196 | 0.63 | TAS1R3 (0.51) | HDAC8ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL13801654 | 0.63 | KDM4E (0.58) | HDAC8ALDH1A1MAPTLMNACRHBP | |
| SCHEMBL2973035 | 0.63 | ALOX15 (0.40) | ALOX15HDAC8ALDH1A1MAPTLMNA | |
| SCHEMBL13801653 | 0.63 | PDE4A (0.41) | ALOX15MAPTCA12CA1CA2 | |
| SCHEMBL18292041 | 0.62 | CA1 (0.65) | CA12CA1CA2CA7CA13 | |
| SCHEMBL18829768 | 0.62 | HDAC8 (0.43) | HDAC8ALDH1A1MAPTLMNACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156441-A1 | Cycloalkyl phenylenediamines as deposit control agents for lubricants | GREAT LAKES CHEMICAL GLOBAL, INC. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156441-A1 | Cycloalkyl phenylenediamines as deposit control agents for lubricants | C5, C9, C1S | ALOX15 65/4885HDAC8 4804/4885ALDH1A1 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.