SCHEMBL4560591

SCHEMBL4560591

CCCCCCCCCCCCCCCC(=O)C(N)(CCCN)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 11/20 0.46
CES1 P23141 7/20 0.46
CES2 O00748 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CYP1A2 P05177 1/20 0.46
PPARG P37231 5/20 0.42
PPARD Q03181 5/20 0.42
PPARA Q07869 5/20 0.42
HDAC11 Q96DB2 4/20 0.42
TSHR P16473 3/20 0.42
GPR84 Q9NQS5 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TLR2 O60603 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
FABP4 P15090 2/20 0.42
PTPN1 P18031 2/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
SLC22A8 Q8TCC7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27658073 1.00 FAAH (0.46) FAAHCES1CES2MEN1KMT2A
SCHEMBL4560589 1.00 FAAH (0.46) FAAHCES1CES2MEN1KMT2A
SCHEMBL27658074 1.00 FAAH (0.46) FAAHCES1CES2MEN1KMT2A
SCHEMBL4560590 1.00 FAAH (0.46) FAAHCES1CES2MEN1KMT2A
SCHEMBL27678222 0.95 FAAH (0.44) FAAHCES1CES2MEN1KMT2A
SCHEMBL8142182 0.95 FAAH (0.44) FAAHCES1CES2MEN1KMT2A
SCHEMBL1555760 0.95 FAAH (0.44) FAAHCES1CES2MEN1KMT2A
SCHEMBL1555759 0.95 FAAH (0.44) FAAHCES1CES2MEN1KMT2A
SCHEMBL27678220 0.95 FAAH (0.44) FAAHCES1CES2MEN1KMT2A
SCHEMBL27678221 0.95 FAAH (0.44) FAAHCES1CES2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3662907-B1 ANTI-AGING OR SKIN-REGENERATING COMPOSITION COMPRISING PIPERONYLIC ACID AS EFFECTIVE INGREDIENT HESED BIO CO LTD (KR) 2024-04-17 EP disclosed
EP-4344696-A1 FUNCTIONAL COMPOSITION FOR ALOPECIA COMPRISING CENTIPEDA MINIMA-DERIVED EXTRACT D-Nature Co., Ltd. (KR) 2024-04-03 EP disclosed
US-11896706-B2 Composition for preventing hair loss or promoting hair growth, comprising, as active ingredient, mixed extract of cucumber, eggplant and snail extracts as active ingredient OGADAL INC. (KR) 2024-02-13 US disclosed
EP-4234683-A1 METHOD FOR CONSTRUCTION OF ATOPIC DERMATITIS MODEL BY USING PLURIPOTENT STEM CELL-DERIVED SKIN ORGANOID Kangstem Biotech Co., Ltd. (KR) 2023-08-30 EP disclosed
CN-116648264-A Pharmaceutical composition for long-term storage of liquid formulations of botulinum toxin ATGC 股份有限公司 2023-08-25 CN disclosed
CN-111356674-B Novel ceramide-like compounds having improved stability and compositions comprising the same 爱敬产业株式会社 2022-12-23 CN disclosed
CN-115337242-A Traditional Chinese medicine composition, extract, preparation method and application thereof, cosmetics and medicines 新生活化妆品科技(上海)有限公司 2022-11-15 CN disclosed
CN-115297879-A Topical composition comprising arillus longan combined crude drug extract for regenerating skin and treating or improving skin wound, and its application (株)美迪合伙来音 2022-11-04 CN disclosed
CN-115297880-A Topical composition comprising extract of crude drug comprising arillus longan for treating or improving skin ulcer, and its application (株)美迪合伙来音 2022-11-04 CN disclosed
CN-115279387-A Topical composition comprising arillus longan combined crude drug extract for inhibiting TSLP and treating or improving skin inflammation diseases, and its application (株)美迪合伙来音 2022-11-01 CN disclosed
US-11439577-B2 Anti-aging or skin-regenerating composition comprising piperonylic acid as effective ingredient Hesed Bio Co., Ltd. (KR) 2022-09-13 US disclosed
CN-114126607-A Composition comprising gossypetin for preventing or treating neurodegenerative diseases 诺代谢健康 2022-03-01 CN disclosed
US-20210100728-A1 ANTI-AGING OR SKIN-REGENERATING COMPOSITION COMPRISING PIPERONYLIC ACID AS EFFECTIVE INGREDIENT Hesed Bio Co., Ltd. (KR) 2021-04-08 US disclosed
EP-3662907-A1 ANTI-AGING OR SKIN-REGENERATING COMPOSITION COMPRISING PIPERONYLIC ACID AS EFFECTIVE INGREDIENT Hesed Bio Co., Ltd. (KR) 2020-06-10 EP disclosed
US-20160221921-A1 SKIN WHITENING AGENT CONTAINING NOVEL CYCLIC COMPOUND RNS CO.,LTD. (KR) 2016-08-04 US disclosed
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF RNS CO.,LTD. (KR) 2015-10-08 US disclosed
WO-2012063973-A1 ANTIOXIDANT COMPOSITION COMPRISING OXIDIZED GLUTATHIONE KYOWA HAKKO BIO CO., LTD. (JP) 2012-05-18 WO disclosed
US-20030211183-A1 Skin-improving agent KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211183-A1 Skin-improving agent CUTA, PCLAF, DSG1 FAAH 1680/4885CES1 2540/4885CES2 3216/4885
US-11439577-B2 Anti-aging or skin-regenerating composition comprising piperonylic acid as effective ingredient EGFR, PDGFA, CUTA FAAH 1477/4885CES1 4557/4885CES2 3741/4885
US-20210100728-A1 ANTI-AGING OR SKIN-REGENERATING COMPOSITION COMPRISING PIPERONYLIC ACID AS EFFECTIVE INGREDIENT EGFR, PDGFA, CUTA FAAH 1477/4885CES1 4557/4885CES2 3741/4885
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF HRH3, CBR3, H1-0 FAAH 203/4885CES1 1404/4885CES2 665/4885
US-20160221921-A1 SKIN WHITENING AGENT CONTAINING NOVEL CYCLIC COMPOUND H1-10, HCN1, HCN4 FAAH 913/4885CES1 3027/4885CES2 1588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.