Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | IL1B | P01584 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560684 | 0.78 | ADORA3 (0.35) | HCAR1ALDH1A1SRCPOLBADORA3 | |
| SCHEMBL14441125 | 0.69 | ALDH1A1 (0.45) | ALDH1A1MAPK1PDE7APDE7BADORA3 | |
| SCHEMBL14336976 | 0.68 | ALDH1A1 (0.36) | ALDH1A1LMNAALBMAPK1MEN1 | |
| SCHEMBL14337030 | 0.68 | MEN1 (0.41) | ALDH1A1LMNAALBMAPK1MEN1 | |
| SCHEMBL17680109 | 0.65 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL14128691 | 0.64 | ALDH1A1 (0.34) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL5438382 | 0.62 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPK1MEN1KMT2A | |
| SCHEMBL8561736 | 0.62 | HCAR1 (0.45) | HCAR1ALDH1A1SRCKMT2A | |
| SCHEMBL13587327 | 0.62 | ALDH1A1 (0.34) | ALDH1A1LMNAALBMAPK1POLB | |
| Hydrochloric Acid SCHEMBL21272879 | 0.61 | PI4KA (0.56) | HCAR1ALDH1A1LMNAMAPK1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298856-A1 | 2,3 Substituted fused bicyclic pyrimidin-4(3H)-ones modulating the function of the vanilliod-1receptor (VR1) | BROWN REBECCA ELIZABETH | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298856-A1 | 2,3 Substituted fused bicyclic pyrimidin-4(3H)-ones modulating the function of the vanilliod-1receptor (VR1) | TRPV1, TRPV2, TRPV4 | HCAR1 87/4885ALDH1A1 897/4885LMNA 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.