Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD5 | P21918 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL28326742 | 0.86 | TSHR (0.40) | CA12CA9CA2TSHRALDH1A1 | |
| Nitric Acid SCHEMBL4562004 | 0.84 | ALDH1A1 (0.44) | CA5ACA5BCA12CA9TSHR | |
| SCHEMBL29071709 | 0.83 | TSHR (0.38) | CA12CA9CA2TSHRALDH1A1 | |
| Nitric Acid SCHEMBL29142702 | 0.83 | ALOX15 (0.35) | CA5ACA5BALDH1A1 | |
| Nitric Acid SCHEMBL27715877 | 0.81 | CA5A (0.42) | CA5ACA5BCA12CA9CA2 | |
| Nitric Acid SCHEMBL7752143 | 0.80 | ALDH1A1 (0.48) | CA12CA9CA2ALDH1A1CA1 | |
| Nitric Acid SCHEMBL11311996 | 0.80 | ALDH1A1 (0.48) | CA12CA9CA2ALDH1A1CA1 | |
| Nitric Acid SCHEMBL28881954 | 0.80 | ALDH1A1 (0.48) | CA12CA9CA2ALDH1A1CA1 | |
| Nitric Acid SCHEMBL28881964 | 0.80 | ALDH1A1 (0.48) | CA12CA9CA2ALDH1A1CA1 | |
| Butane SCHEMBL18261807 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790135-B | Preparation method of benzoyl formic acid | 浙江理工大学 | 2023-12-19 | — | — | CN | claimed |
| CN-114790135-A | Preparation method of benzoylformic acid | 浙江理工大学 | 2022-07-26 | — | — | CN | claimed |
| CN-114790135-B | Preparation method of benzoyl formic acid | 浙江理工大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-114790135-A | Preparation method of benzoylformic acid | 浙江理工大学 | 2022-07-26 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |