Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1494601 | 0.98 | TSHR (0.45) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL65529 | 0.94 | TSHR (0.45) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL4925781 | 0.92 | TSHR (0.41) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL18393958 | 0.91 | THRB (0.42) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL9566721 | 0.89 | THRB (0.43) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL5959040 | 0.88 | THRB (0.40) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL51592 | 0.87 | TSHR (0.50) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL9013033 | 0.86 | ALDH1A1 (0.51) | TSHRTHRBALDH1A1HSD17B10TP53 | |
| SCHEMBL2763614 | 0.85 | LMNA (0.49) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL10611903 | 0.85 | ALDH1A1 (0.50) | TSHRTHRBALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802662-A4 | SURFACE POLYMERISATION PROCESS AND POLYMER PRODUCT USING RAFT AGENT | UNIV SYDNEY (AU) | 2009-08-26 | — | — | EP | disclosed |
| EP-1802662-A1 | SURFACE POLYMERISATION PROCESS AND POLYMER PRODUCT USING RAFT AGENT | The University of Sydney (AU) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006037161-A1 | SURFACE POLYMERISATION PROCESS AND POLYMER PRODUCT USING RAFT AGENT | THE UNIVERSITY OF SYDNEY (AU) | 2006-04-13 | — | — | WO | disclosed |