SCHEMBL1494601

SCHEMBL1494601

C=C(C)C(=O)OCC(C)(CO)COC(=O)C(=C)C

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
THRB P10828 1/20 0.42
ALDH1A1 P00352 3/20 0.40
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4562564 0.98 TSHR (0.44) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL65529 0.96 TSHR (0.45) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL4925781 0.94 TSHR (0.41) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL18393958 0.93 THRB (0.42) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL9566721 0.90 THRB (0.43) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL5959040 0.89 THRB (0.40) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL51592 0.89 TSHR (0.50) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL9013033 0.88 ALDH1A1 (0.51) TSHRTHRBALDH1A1HSD17B10TP53
SCHEMBL2763614 0.87 LMNA (0.49) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL10611903 0.87 ALDH1A1 (0.50) TSHRTHRBALDH1A1HSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121987-A Water-based 3D printing material and preparation method and application thereof 李立 2021-07-16 CN claimed
CN-105669938-A Waterborne radiation-supportive curing polyurethane acrylate combination, preparation method and coating 万华化学集团股份有限公司 2016-06-15 CN claimed
CN-101906235-B Radiation curing composition for light guide fiber CHINA NAT OFFSHORE OIL CORP 2012-10-10 CN claimed
CN-101906235-A Radiation curing composition for light guide fiber CHINA NAT OFFSHORE OIL CORP 2010-12-08 CN claimed
EP-1498098-B1 Adhesive composition with decreased polarity upon polymerization 3M ESPE AG (DE) 2006-05-03 EP claimed
US-4678846-A HIGH AND LOW MOLECULAR WEIGHT TH. GOLDSCHMIDT AG (DE) 1987-07-07 US claimed
CN-121574490-A Novel silicon hydrogel contact lens and preparation method thereof 华诺森(武汉)生物医药技术有限公司 2026-02-27 CN disclosed
US-20260015438-A1 Photopolymerizable Compositions Including a Polyurethane Methacrylate Polymer Prepared Using a Polycarbonate Diol, Articles, and Methods SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-15 US disclosed
US-12421336-B2 Orthodontic articles comprising cured free-radically polymerizable composition with improved strength in aqueous environment Solventum Intellectual Properties (US) 2025-09-23 US disclosed
EP-3782599-B1 DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2025-09-17 EP disclosed
US-12351668-B2 Orthodontic articles comprising polymerized composition with pendent cyclic moieties, methods, and polymerizable compositions SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-07-08 US disclosed
EP-3973007-B1 ORTHODONTIC ARTICLES COMPRISING POLYMERIZED COMPOSITION WITH PENDENT CYCLIC MOIETIES, METHODS, AND POLYMERIZABLE COMPOSITIONS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-06-25 EP disclosed
US-12194494-B2 Method for applying multi-layered coat onto automotive component molded product NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) 2025-01-14 US disclosed
US-4038257-A HIGH STRENGTH, CORROSION RESISTANCE TOYO BOSEKI KABUSHIKI KAISHA (JA) 1977-07-26 US disclosed
US-4037021-A Photopolymerizable compositions containing a keto dioxolane as the photosensitizer SUN CHEMICAL CORPORATION (US) 1977-07-19 US disclosed
US-4022674-A Photopolymerizable compounds and compositions comprising the product of the reaction of a monomeric ester and a polycarboxy-substituted benzophenone SUN CHEMICAL CORPORATION (US) 1977-05-10 US disclosed
US-4004998-A Photopolymerizable compounds and compositions comprising the product of the reaction of a hydroxy-containing ester and a monocarboxy-substituted benzophenone SUN CHEMICAL CORPORATION (US) 1977-01-25 US disclosed
US-3992363-A POLY(TRICHLOROACETYL-STYRENE) SUN CHEMICAL CORPORATION (US) 1976-11-16 US disclosed
US-3978133-A UNSATURATED MONOMERS, POLYHALOACETYL SUN CHEMICAL CORPORATION (US) 1976-08-31 US disclosed
US-3944509-A UNSATURATED, PHOTOPOLYMERIZABLE MONOMERS SUN CHEMICAL CORPORATION (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421336-B2 Orthodontic articles comprising cured free-radically polymerizable composition with improved strength in aqueous environment ELL, PCNA, PAM TSHR 4442/4885THRB 4328/4885ALDH1A1 411/4885
US-20260015438-A1 Photopolymerizable Compositions Including a Polyurethane Methacrylate Polymer Prepared Using a Polycarbonate Diol, Articles, and Methods HTR3D, EIF3D, MYD88 TSHR 4017/4885THRB 1938/4885ALDH1A1 1135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.