SCHEMBL65529

SCHEMBL65529

C=C(C)C(=O)OCC(C)(CO)CO

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
THRB P10828 1/20 0.42
ALDH1A1 P00352 3/20 0.40
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1494601 0.96 TSHR (0.45) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL4562564 0.94 TSHR (0.44) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL18393958 0.93 THRB (0.42) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL4925781 0.90 TSHR (0.41) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL9566721 0.90 THRB (0.43) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL51592 0.89 TSHR (0.50) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL2763614 0.87 LMNA (0.49) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL5959040 0.86 THRB (0.40) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL9013033 0.84 ALDH1A1 (0.51) TSHRTHRBALDH1A1HSD17B10TP53
SCHEMBL10802310 0.83 THRB (0.41) TSHRTHRBALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5315 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12012355-B2 Glass substrate multilayer structure, manufacturing method thereof, and flexible display panel including the same SK INNOVATION CO., LTD. (KR) 2024-06-18 US claimed
US-20240108555-A1 UNREACTIVE TRANSFER SPLINTS VOCO GMBH (DE) 2024-04-04 US claimed
EP-3482740-B1 DENTAL PHOTOPOLYMERIZABLE COMPOSITION G C DENTAL IND CORP (JP) 2024-03-27 EP claimed
EP-4338702-A1 NON-REACTIVE TRANSFER RAILS VOCO GmbH (DE) 2024-03-20 EP claimed
WO-2024018039-A1 ACRYLIC COPOLYMERS IMPARTING LOW YELLOWING AFTER PHOTOCURING ARKEMA FRANCE (FR) 2024-01-25 WO claimed
WO-2024018041-A1 OLIGOMERS COMPRISING POLYMERIZED HIGH-TG MONOMERS ARKEMA FRANCE (FR) 2024-01-25 WO claimed
WO-2023237595-A1 COMPOSITION BASED ON A POLYMERIZABLE COMPONENT AND A THIXOTROPIC ADDITIVE ARKEMA FRANCE (FR) 2023-12-14 WO claimed
US-20230340202-A9 Polyamideimide Film-Forming Composition, Method of Preparing the Same, and Use Thereof SK IE TECHNOLOGY CO., LTD. (KR) 2023-10-26 US claimed
US-20230098970-A1 Polyamideimide Film-Forming Composition, Method of Preparing the Same, and Use Thereof SK INNOVATION CO LTD (KR) 2023-03-30 US claimed
WO-2023000996-A1 POLYMERIZABLE MONOMER COMPOSITION FOR DENTAL RESTORATION, PREPARATION METHOD THEREFOR AND USE THEREOF 爱迪特(秦皇岛)科技股份有限公司 2023-01-26 WO claimed
EP-0494679-A1 Heat-shrinkable tubing and process for producing the same SUMITOMO ELECTRIC INDUSTRIES, LIMITED (JP) 1992-07-15 EP claimed
EP-0493631-A1 Artificial marble composition SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-07-08 EP claimed
US-5126228-A Presensitized FUJI PHOTO FILM, CO., LTD. (JP) 1992-06-30 US claimed
US-5059511-A Curable silicone rubber layer on light sensitive resin of (meth)acryloyl and allyl monomers, photoinitiators FUJI PHOTO FILM CO., LTD. (JP) 1991-10-22 US claimed
EP-0386777-A2 PS plate for use in making lithographic printing plate requiring no dampening water Fuji Photo Film Co., Ltd. (JP) 1990-09-12 EP claimed
EP-0254799-B1 (METH)ACRYLIC ESTER MODIFIED ORGANOPOLYSILOXANES, PROCESS FOR MAKING THEM AND THEIR USE AS ADHESIVE COATING COMPOSITIONS Th. Goldschmidt AG (DE) 1990-06-13 EP claimed
US-4921930-A ABRASION RESISTANT POLYESTERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-01 US claimed
US-4910281-A Polyurethane from diol and diisocyanate MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-03-20 US claimed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US claimed
US-4447328-A Filler for liquid chromatography and method for separating water-soluble substances using said filler Sekisu Kagaku Kogyo Kabushiki Kaisha (JP) 1984-05-08 US claimed